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IPR001253 is a Translation initiation factor 1A (eIF-1A).
<p>Eukaryotic translation initiation factor A (eIF-1A) (formerly known as eiF-4C) is a protein that seems to be required for maximal rate of protein biosynthesis. It enhances ribosome dissociation into subunits and stabilises the binding of the initiator Met-tRNA to 40S ribosomal subunits [[cite:PUB00002919]]. The archaea possess an eIF-1A homologue.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. | ||
| Biological process | Translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable RNA-binding protein EIF1AD-like [Cicer arietinum] gi|502163627|ref|XP_004512897.1| | 9 | ||
| – | PREDICTED: probable RNA-binding protein EIF1AD-like [Cicer arietinum] gi|502163627|ref|XP_004512897.1| | 9 | ||
| – | PREDICTED: eukaryotic translation initiation factor 1A-like [Cicer arietinum] gi|502084002|ref|XP_004487629.1| | 13 | ||
| – | PREDICTED: eukaryotic translation initiation factor 1A-like [Cicer arietinum] gi|502084002|ref|XP_004487629.1| | 14 | ||
| – | Eukaryotic translation initiation factor 1A; TAIR: AT2G40780.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q58CY2|EIF1A_BOVIN Probable RNA-binding protein EIF1AD; TrEMBL-Plants: tr|A0A0L9UEA0|A0A0L9UEA0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0305200 | 11 | ||
| – | Eukaryotic translation initiation factor 1A; TAIR: AT2G40780.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q58CY2|EIF1A_BOVIN Probable RNA-binding protein EIF1AD; TrEMBL-Plants: tr|A0A0L9UEA0|A0A0L9UEA0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0305200 | 11 | ||
| – | Eukaryotic translation initiation factor 1A; TAIR: AT2G04520.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|P56331|IF1A_ONOVI Eukaryotic translation initiation factor 1A; TrEMBL-Plants: tr|I3SHT8|I3SHT8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0392400 | 16 | ||
| – | Eukaryotic translation initiation factor 1A; TAIR: AT2G04520.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|P56331|IF1A_ONOVI Eukaryotic translation initiation factor 1A; TrEMBL-Plants: tr|I3T689|I3T689_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0390300 | 16 | ||
| – | Eukaryotic translation initiation factor 1A; TAIR: AT2G40780.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q3THJ3|EIF1A_MOUSE Probable RNA-binding protein EIF1AD; TrEMBL-Plants: tr|V7AS60|V7AS60_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0337600 | 11 | ||
| – | Eukaryotic translation initiation factor 1A; TAIR: AT2G40780.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q3THJ3|EIF1A_MOUSE Probable RNA-binding protein EIF1AD; TrEMBL-Plants: tr|V7AS60|V7AS60_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0337600 | 11 | ||
| – | Eukaryotic translation initiation factor 1A; TAIR: AT2G40780.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|Q3THJ3|EIF1A_MOUSE Probable RNA-binding protein EIF1AD; TrEMBL-Plants: tr|V7AS60|V7AS60_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0337600 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 9.09 |