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IPR003111 is a Lon protease, N-terminal domain.
<p>This entry represents the N-terminal substrate-binding domain of the Lon protease. This ATP-dependent enzyme, a serine peptidase belonging to the MEROPS peptidase family S16, is conserved in archaeal, bacterial and eukaryotic organisms and catalyses rapid turnover of short-lived regulatory proteins and many damaged or denatured proteins. In eukaryotes, the majority of the proteins are located in the mitochondrial matrix [[cite:PUB00004808], [cite:PUB00011879]]. In yeast, Pim1, is located in the mitochondrial matrix and required for mitochondrial function. It is constitutively expressed but is increased after thermal stress, suggesting that Pim1 may play a role in the heat shock response [[cite:PUB00002870]].</p> <p>The structure of this domain has been determined and it represents a general protein and polypeptide interaction domain [[cite:PUB00039341], [cite:PUB00055624], [cite:PUB00075692], [cite:PUB00099721]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: lon protease homolog 2, peroxisomal-like [Cicer arietinum] gi|502152569|ref|XP_004508987.1| | 9 | ||
| – | PREDICTED: lon protease homolog 1, mitochondrial-like [Glycine max] gi|356533540|ref|XP_003535321.1| | 32 | ||
| – | PREDICTED: LON peptidase N-terminal domain and RING finger protein 1-like [Glycine max] gi|356508525|ref|XP_003523006.1| | 23 | ||
| – | PREDICTED: protein cereblon-like [Glycine max] gi|356510047|ref|XP_003523752.1| | 11 | ||
| – | PREDICTED: lon protease 2-like [Cicer arietinum] gi|502131384|ref|XP_004500968.1| | 11 | ||
| – | PREDICTED: lon protease 2-like [Cicer arietinum] gi|502131384|ref|XP_004500968.1| | 10 | ||
| – | PREDICTED: lon protease homolog 2, peroxisomal-like [Cicer arietinum] gi|502160472|ref|XP_004511756.1| | 32 | ||
| – | PREDICTED: lon protease homolog 2, peroxisomal-like [Cicer arietinum] gi|502160472|ref|XP_004511756.1| | 30 | ||
| – | PREDICTED: lon protease 2-like [Glycine max] gi|356510000|ref|XP_003523729.1| | 7 | ||
| – | RING finger protein 141; TAIR: AT1G18660.1 zinc finger (C3HC4-type RING finger) family protein; Swiss-Prot: sp|D3YY23|LONF1_MOUSE LON peptidase N-terminal domain and RING finger protein 1; TrEMBL-Plants: tr|K7KKL8|K7KKL8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0194200 | 24 | ||
| – | ATP-dependent protease LA (Lon) domain protein; TAIR: AT2G25740.1 ATP-dependent protease La (LON) domain protein; Swiss-Prot: sp|Q68EH9|CRBN_DANRE Protein cereblon; TrEMBL-Plants: tr|A0A0L9UH25|A0A0L9UH25_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0409100 | 17 | ||
| – | Lon protease homolog; TAIR: AT5G47040.1 lon protease 2; Swiss-Prot: sp|O04979|LONP2_SPIOL Lon protease homolog 2, peroxisomal; TrEMBL-Plants: tr|G7JYP5|G7JYP5_MEDTR Lon protease homolog 2, peroxisomal; Found in the gene: LotjaGi2g1v0417300 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G47040.1 lon protease 2; Swiss-Prot: sp|O04979|LONP2_SPIOL Lon protease homolog 2, peroxisomal; TrEMBL-Plants: tr|G7JYP5|G7JYP5_MEDTR Lon protease homolog 2, peroxisomal; Found in the gene: LotjaGi2g1v0417300 | 36 | ||
| – | Lon protease; TAIR: AT1G75460.1 ATP-dependent protease La (LON) domain protein; Swiss-Prot: sp|Q2IIK1|LON_ANADE Lon protease; TrEMBL-Plants: tr|I1JT74|I1JT74_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0189200_LC | 9 | ||
| – | Lon protease homolog; TAIR: AT1G75460.1 ATP-dependent protease La (LON) domain protein; Swiss-Prot: sp|Q2IIK1|LON_ANADE Lon protease; TrEMBL-Plants: tr|I1JT74|I1JT74_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0292700_LC | 9 | ||
| – | ATP-dependent protease LA (Lon) domain protein; TAIR: AT2G25740.1 ATP-dependent protease La (LON) domain protein; Swiss-Prot: sp|Q68EH9|CRBN_DANRE Protein cereblon; TrEMBL-Plants: tr|A0A1J7I6V9|A0A1J7I6V9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0164900 | 17 | ||
| – | Protein cereblon; TAIR: AT2G25740.1 ATP-dependent protease La (LON) domain protein; Swiss-Prot: sp|Q68EH9|CRBN_DANRE Protein cereblon; TrEMBL-Plants: tr|G7I262|G7I262_MEDTR ATP-dependent protease LA (Lon) domain protein; Found in the gene: LotjaGi4g1v0164900 | 14 | ||
| – | Lon protease homolog; TAIR: AT5G47040.1 lon protease 2; Swiss-Prot: sp|O04979|LONP2_SPIOL Lon protease homolog 2, peroxisomal; TrEMBL-Plants: tr|A0A072UQE3|A0A072UQE3_MEDTR Lon protease homolog 2, peroxisomal; Found in the gene: LotjaGi4g1v0191600 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G47040.1 lon protease 2; Swiss-Prot: sp|O04979|LONP2_SPIOL Lon protease homolog 2, peroxisomal; TrEMBL-Plants: tr|A0A072UQE3|A0A072UQE3_MEDTR Lon protease homolog 2, peroxisomal; Found in the gene: LotjaGi4g1v0191600 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G47040.1 lon protease 2; Swiss-Prot: sp|O04979|LONP2_SPIOL Lon protease homolog 2, peroxisomal; TrEMBL-Plants: tr|A0A072UQE3|A0A072UQE3_MEDTR Lon protease homolog 2, peroxisomal; Found in the gene: LotjaGi4g1v0191600 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G47040.1 lon protease 2; Swiss-Prot: sp|O04979|LONP2_SPIOL Lon protease homolog 2, peroxisomal; TrEMBL-Plants: tr|A0A072UQE3|A0A072UQE3_MEDTR Lon protease homolog 2, peroxisomal; Found in the gene: LotjaGi4g1v0191600 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G47040.1 lon protease 2; Swiss-Prot: sp|O04979|LONP2_SPIOL Lon protease homolog 2, peroxisomal; TrEMBL-Plants: tr|A0A072UQE3|A0A072UQE3_MEDTR Lon protease homolog 2, peroxisomal; Found in the gene: LotjaGi4g1v0191600 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G26860.1 lon protease 1; Swiss-Prot: sp|P93648|LONM_MAIZE Lon protease homolog, mitochondrial; TrEMBL-Plants: tr|A0A0S3SQJ4|A0A0S3SQJ4_PHAAN Lon protease homolog, mitochondrial; Found in the gene: LotjaGi5g1v0229900 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G26860.1 lon protease 1; Swiss-Prot: sp|P93648|LONM_MAIZE Lon protease homolog, mitochondrial; TrEMBL-Plants: tr|A0A0S3SQJ4|A0A0S3SQJ4_PHAAN Lon protease homolog, mitochondrial; Found in the gene: LotjaGi5g1v0229900 | 36 | ||
| – | Lon protease homolog; TAIR: AT5G26860.1 lon protease 1; Swiss-Prot: sp|P93648|LONM_MAIZE Lon protease homolog, mitochondrial; TrEMBL-Plants: tr|A0A0S3SQJ4|A0A0S3SQJ4_PHAAN Lon protease homolog, mitochondrial; Found in the gene: LotjaGi5g1v0229900 | 37 | ||
| – | Lon protease homolog; TAIR: AT5G26860.1 lon protease 1; Swiss-Prot: sp|P93648|LONM_MAIZE Lon protease homolog, mitochondrial; TrEMBL-Plants: tr|A0A0S3SQJ4|A0A0S3SQJ4_PHAAN Lon protease homolog, mitochondrial; Found in the gene: LotjaGi5g1v0229900 | 37 | ||
| – | Lon protease homolog; TAIR: AT5G26860.1 lon protease 1; Swiss-Prot: sp|P93648|LONM_MAIZE Lon protease homolog, mitochondrial; TrEMBL-Plants: tr|A0A0S3SQJ4|A0A0S3SQJ4_PHAAN Lon protease homolog, mitochondrial; Found in the gene: LotjaGi5g1v0229900 | 38 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 3.70 |