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IPR003956

Source: InterPro

Description

IPR003956 is a Transcription factor, NFYB/HAP3, conserved site.

<p>The CCAAT-binding factor (CBF, of NFY) is a mammalian transcription factor that binds to a CCAAT motif in the promoters of a wide variety of genes, including type I collagen and albumin. The factor is a heteromeric complex of A and B subunits, both of which are required for DNA-binding [[cite:PUB00002598], [cite:PUB00004401]]. The subunits can interact in the absence of DNA-binding, conserved regions in each being important in mediating this interaction.</p> <p>The A subunit can be split into 3 domains on the basis of sequence similarity, a non-conserved N-terminal 'A domain'; a highly-conserved central 'B domain' involved in DNA-binding; and a C-terminal 'C domain', which contains a number of glutamine and acidic residues involved in protein-protein interactions [[cite:PUB00004401]]. The A subunit shows striking similarity to the HAP3 subunit of the yeast CCAAT-binding heterotrimeric transcription factor [[cite:PUB00004401], [cite:PUB00003767]]. The Kluyveromyces lactis HAP3 protein has been predicted to contain a 4-cysteine zinc finger, which is thought to be present in similar HAP3 and CBF subunit A proteins, in which the third cysteine is replaced by a serine [[cite:PUB00003767]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005634
Cellular component Nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Subterm of
GO:0006355
Biological process Regulation of transcription, DNA-templated Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
Subterm of
Regulates
GO:0043565
Molecular function Sequence-specific DNA binding Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
Subterm of

Associated Lotus transcripts 29

Transcript Name Description Predicted domains Domain count
Lj0g3v0209729.1
– PREDICTED: nuclear transcription factor Y subunit B-5-like [Cicer arietinum] gi|502151779|ref|XP_004508609.1|
Domains
11
Lj2g3v2087990.1
– PREDICTED: nuclear transcription factor Y subunit B-6 [Glycine max] gi|356576945|ref|XP_003556590.1|
Domains
11
Lj4g3v2365210.1
– PREDICTED: nuclear transcription factor Y subunit B-5-like [Glycine max] gi|356532577|ref|XP_003534848.1|
Domains
11
Lj4g3v2799410.1
– PREDICTED: nuclear transcription factor Y subunit B-7-like [Glycine max] gi|356511129|ref|XP_003524282.1|
Domains
12
Lj4g3v2825520.1
– PREDICTED: nuclear transcription factor Y subunit B-7-like [Glycine max] gi|356511186|ref|XP_003524310.1|
Domains
11
Lj6g3v1584620.1
– PREDICTED: nuclear transcription factor Y subunit B-8-like [Glycine max] gi|356537473|ref|XP_003537251.1|
Domains
10
Lj6g3v1720580.1
– PREDICTED: nuclear transcription factor Y subunit B-3-like [Glycine max] gi|356555763|ref|XP_003546199.1|
Domains
11
Lj6g3v1720580.2
– PREDICTED: nuclear transcription factor Y subunit B-3-like [Glycine max] gi|356555763|ref|XP_003546199.1|
Domains
11
LotjaGi1g1v0016000.1
– Nuclear transcription factor Y protein; TAIR: AT4G14540.1 nuclear factor Y, subunit B3; Swiss-Prot: sp|Q75IZ7|NFYB8_ORYSJ Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0L9VBC0|A0A0L9VBC0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0016000
Domains
11
LotjaGi1g1v0321200.1
– Nuclear transcription factor Y subunit B; TAIR: AT2G13570.1 nuclear factor Y, subunit B7; Swiss-Prot: sp|Q9SIT9|NFYB7_ARATH Nuclear transcription factor Y subunit B-7; TrEMBL-Plants: tr|I1K511|I1K511_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0321200
Domains
11
LotjaGi1g1v0694000_LC.1
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0L9U847|A0A0L9U847_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0694000_LC
Domains
11
LotjaGi1g1v0694000_LC.2
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0B2PJ97|A0A0B2PJ97_GLYSO Nuclear transcription factor Y subunit B-8; Found in the gene: LotjaGi1g1v0694000_LC
Domains
16
LotjaGi1g1v0694000_LC.3
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0S3RYL3|A0A0S3RYL3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0694000_LC
Domains
16
LotjaGi1g1v0694000_LC.4
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0S3RYL3|A0A0S3RYL3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0694000_LC
Domains
16
LotjaGi2g1v0439900.1
– Nuclear transcription factor Y subunit B; TAIR: AT1G21970.1 Histone superfamily protein; Swiss-Prot: sp|Q9SFD8|NFYB9_ARATH Nuclear transcription factor Y subunit B-9; TrEMBL-Plants: tr|I1NCV5|I1NCV5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0439900
Domains
11
LotjaGi4g1v0005900.1
– Nuclear transcription factor Y protein; TAIR: AT5G47670.1 nuclear factor Y, subunit B6; Swiss-Prot: sp|Q84W66|NFYB6_ARATH Nuclear transcription factor Y subunit B-6; TrEMBL-Plants: tr|B5KMT1|B5KMT1_9FABA Transcription factor LEC1-B; Found in the gene: LotjaGi4g1v0005900
Domains
11
LotjaGi4g1v0343900.1
– Nuclear transcription factor Y subunit B; TAIR: AT2G47810.1 nuclear factor Y, subunit B5; Swiss-Prot: sp|O82248|NFYB5_ARATH Nuclear transcription factor Y subunit B-5; TrEMBL-Plants: tr|A0A0B2QYD6|A0A0B2QYD6_GLYSO Nuclear transcription factor Y subunit B-5; Found in the gene: LotjaGi4g1v0343900
Domains
11
LotjaGi4g1v0402200.1
– Nuclear transcription factor Y subunit B; TAIR: AT4G14540.1 nuclear factor Y, subunit B3; Swiss-Prot: sp|Q0J7P4|HD5_ORYSJ Nuclear transcription factor Y subunit B-11; TrEMBL-Plants: tr|A0A0B2S259|A0A0B2S259_GLYSO Nuclear transcription factor Y subunit B-3; Found in the gene: LotjaGi4g1v0402200
Domains
11
LotjaGi4g1v0410500.1
– Nuclear transcription factor Y subunit B; TAIR: AT2G13570.1 nuclear factor Y, subunit B7; Swiss-Prot: sp|Q9SIT9|NFYB7_ARATH Nuclear transcription factor Y subunit B-7; TrEMBL-Plants: tr|I1K511|I1K511_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0410500
Domains
11
LotjaGi5g1v0074500.1
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0S3RYL3|A0A0S3RYL3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0074500
Domains
11
LotjaGi5g1v0074500.2
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0S3RYL3|A0A0S3RYL3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0074500
Domains
11
LotjaGi5g1v0074500.3
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A1J7GR83|A0A1J7GR83_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0074500
Domains
11
LotjaGi5g1v0161200.1
– Nuclear transcription factor Y subunit B; TAIR: AT2G38880.10 nuclear factor Y, subunit B1; Swiss-Prot: sp|Q9SLG0|NFYB1_ARATH Nuclear transcription factor Y subunit B-1; TrEMBL-Plants: tr|B9SD43|B9SD43_RICCO Ccaat-binding transcription factor subunit A, putative; Found in the gene: LotjaGi5g1v0161200
Domains
11
LotjaGi5g1v0161200.2
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|E0WC42|E0WC42_SOYBN CCAAT-binding transcription factor family protein; Found in the gene: LotjaGi5g1v0161200
Domains
11
LotjaGi5g1v0161200.3
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|E0WC42|E0WC42_SOYBN CCAAT-binding transcription factor family protein; Found in the gene: LotjaGi5g1v0161200
Domains
11
LotjaGi5g1v0161200.4
– Nuclear transcription factor Y subunit B; TAIR: AT2G37060.1 nuclear factor Y, subunit B8; Swiss-Prot: sp|Q8VYK4|NFYB8_ARATH Nuclear transcription factor Y subunit B-8; TrEMBL-Plants: tr|A0A0B2NVD4|A0A0B2NVD4_GLYSO Nuclear transcription factor Y subunit B-8; Found in the gene: LotjaGi5g1v0161200
Domains
11
LotjaGi5g1v0161200.5
– Nuclear transcription factor Y subunit B; TAIR: AT2G38880.10 nuclear factor Y, subunit B1; Swiss-Prot: sp|Q9SLG0|NFYB1_ARATH Nuclear transcription factor Y subunit B-1; TrEMBL-Plants: tr|A0A0R0I2W3|A0A0R0I2W3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0161200
Domains
11
LotjaGi6g1v0143300.1
– Nuclear transcription factor Y protein; TAIR: AT4G14540.1 nuclear factor Y, subunit B3; Swiss-Prot: sp|O23310|NFYB3_ARATH Nuclear transcription factor Y subunit B-3; TrEMBL-Plants: tr|A0A0L9VBC0|A0A0L9VBC0_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0143300
Domains
11
LotjaGi6g1v0248200.1
– Nuclear transcription factor Y subunit B; TAIR: AT2G47810.1 nuclear factor Y, subunit B5; Swiss-Prot: sp|O82248|NFYB5_ARATH Nuclear transcription factor Y subunit B-5; TrEMBL-Plants: tr|I3TAX6|I3TAX6_MEDTR Nuclear transcription factor Y subunit B18; Found in the gene: LotjaGi6g1v0248200
Domains
11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 3.45