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IPR004549 is a Acetyl-CoA carboxylase, biotin carboxylase.
<p>This family represents the biotin carboxylase subunit found usually as a component of acetyl-CoA carboxylase. Acetyl-CoA carboxylase ([ec:6.4.1.2]) is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase ([ec:6.3.4.14]), and two subunits of carboxyl transferase in a 2:2 complex. In the first step of long-chain fatty acid synthesis, biotin carboxylase catalyses the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-coA. Homologous domains are found in eukaryotic forms of acetyl-CoA carboxylase and in a number of other carboxylases (e.g. pyruvate carboxylase). In some systems, the biotin carboxyl carrier protein and this protein (biotin carboxylase) may be shared by different carboxyltransferases. However, this model is not intended to identify the biotin carboxylase domain of propionyl-coA carboxylase. The model should hit the full length of proteins, except for chloroplast transit peptides in plants. If it hits a domain only of a longer protein, there may be a problem with the identification.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Ligase activity | Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: biotin carboxylase 1, chloroplastic-like [Cicer arietinum] gi|502138858|ref|XP_004503555.1| | 26 | ||
| – | Biotin carboxylase; TAIR: AT5G35360.1 acetyl Co-enzyme a carboxylase biotin carboxylase subunit; Swiss-Prot: sp|B9HBA8|ACCC1_POPTR Biotin carboxylase 1, chloroplastic; TrEMBL-Plants: tr|O23960|O23960_SOYBN Acetyl-CoA carboxylase; Found in the gene: LotjaGi4g1v0439600 | 23 | ||
| – | Biotin carboxylase; TAIR: AT5G35360.1 acetyl Co-enzyme a carboxylase biotin carboxylase subunit; Swiss-Prot: sp|B9HBA8|ACCC1_POPTR Biotin carboxylase 1, chloroplastic; TrEMBL-Plants: tr|O23960|O23960_SOYBN Acetyl-CoA carboxylase; Found in the gene: LotjaGi4g1v0439600 | 23 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00514 | TIGRFAM | 1 | 33.33 |