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IPR011761 is a ATP-grasp fold.
<p>The ATP-grasp superfamily currently includes 17 groups of enzymes, catalysing ATP-dependent ligation of a carboxylate containing molecule to an amino or thiol group-containing molecule [[cite:PUB00020972]]. They contribute predominantly to macromolecular synthesis. ATP-hydrolysis is used to activate a substrate. For example, DD-ligase transfers phosphate from ATP to D-alanine on the first step of catalysis. On the second step the resulting acylphosphate is attacked by a second D-alanine to produce a DD dipeptide following phosphate elimination [[cite:PUB00015340]].</p> <p>The ATP-grasp domain contains three conserved motifs, corresponding to the phosphate binding loop and the Mg(2+) binding site [[cite:PUB00015341]]. The fold is characterised by two α-β subdomains that grasp the ATP molecule between them. Each subdomain provides a variable loop that forms part of the active site, with regions from other domains also contributing to the active site, even though these other domains are not conserved between the various ATP-grasp enzymes [[cite:PUB00015342]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | ATP binding | Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | ||
| Molecular function | Metal ion binding | Interacting selectively and non-covalently with any metal ion. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: phosphoribosylaminoimidazole carboxylase, chloroplastic-like [Glycine max] gi|356535191|ref|XP_003536132.1| | 12 | ||
| – | D-alanine--D-alanine ligase [Medicago truncatula] gi|357506461|ref|XP_003623519.1| | 21 | ||
| – | D-alanine--D-alanine ligase [Medicago truncatula] gi|357506461|ref|XP_003623519.1| | 19 | ||
| – | PREDICTED: phosphoribosylaminoimidazole carboxylase, chloroplastic-like [Glycine max] gi|356535191|ref|XP_003536132.1| | 13 | ||
| – | Carbamoyl-phosphate synthase large chain [Medicago truncatula] gi|357453751|ref|XP_003597156.1| | 32 | ||
| – | PREDICTED: phosphoribosylaminoimidazole carboxylase, chloroplastic-like [Glycine max] gi|356535191|ref|XP_003536132.1| | 30 | ||
| – | D-alanine--D-alanine ligase [Medicago truncatula] gi|357506461|ref|XP_003623519.1| | 22 | ||
| – | D-alanine--D-alanine ligase [Medicago truncatula] gi|357506461|ref|XP_003623519.1| | 21 | ||
| – | Inositol phosphate kinase [Glycine max] gi|351721472|ref|NP_001237466.1| | 8 | ||
| – | PREDICTED: biotin carboxylase 1, chloroplastic-like [Cicer arietinum] gi|502138858|ref|XP_004503555.1| | 26 | ||
| – | PREDICTED: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial-like isoform X2 [Cicer arietinum] gi|502115337|ref|XP_004495179.1| | 33 | ||
| – | Succinyl-CoA ligase beta subunit [Caragana jubata] gi|146215968|gb|ABQ10186.1| | 21 | ||
| – | PREDICTED: phosphoribosylamine--glycine ligase, chloroplastic-like isoform X2 [Cicer arietinum] gi|502123844|ref|XP_004498282.1| | 28 | ||
| – | Acetyl-CoA carboxylase; TAIR: AT1G36160.1 acetyl-CoA carboxylase 1; Swiss-Prot: sp|Q38970|ACC1_ARATH Acetyl-CoA carboxylase 1; TrEMBL-Plants: tr|A0A0R0K6S7|A0A0R0K6S7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0246300 | 46 | ||
| – | Acetyl-CoA carboxylase; TAIR: AT1G36160.1 acetyl-CoA carboxylase 1; Swiss-Prot: sp|Q38970|ACC1_ARATH Acetyl-CoA carboxylase 1; TrEMBL-Plants: tr|A0A0R0K6S7|A0A0R0K6S7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0246300 | 46 | ||
| – | Acetyl-CoA carboxylase; TAIR: AT1G36160.1 acetyl-CoA carboxylase 1; Swiss-Prot: sp|Q38970|ACC1_ARATH Acetyl-CoA carboxylase 1; TrEMBL-Plants: tr|I1JVH6|I1JVH6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0246300 | 46 | ||
| – | Acetyl-CoA carboxylase; TAIR: AT1G36160.1 acetyl-CoA carboxylase 1; Swiss-Prot: sp|Q38970|ACC1_ARATH Acetyl-CoA carboxylase 1; TrEMBL-Plants: tr|A0A0R0K6S7|A0A0R0K6S7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0246300 | 46 | ||
| – | D-alanine--D-alanine ligase; TAIR: AT3G08840.2 D-alanine-D-alanine ligase family; Swiss-Prot: sp|Q6MQ94|DDL_BDEBA D-alanine--D-alanine ligase; TrEMBL-Plants: tr|I1L754|I1L754_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0450300 | 21 | ||
| – | Carbamoyl-phosphate synthase large chain; TAIR: AT1G29900.1 carbamoyl phosphate synthetase B; Swiss-Prot: sp|Q42601|CARB_ARATH Carbamoyl-phosphate synthase large chain, chloroplastic; TrEMBL-Plants: tr|G7IU57|G7IU57_MEDTR Carbamoyl-phosphate synthase large chain; Found in the gene: LotjaGi3g1v0161000 | 36 | ||
| – | Biotin carboxylase; TAIR: AT5G35360.1 acetyl Co-enzyme a carboxylase biotin carboxylase subunit; Swiss-Prot: sp|B9HBA8|ACCC1_POPTR Biotin carboxylase 1, chloroplastic; TrEMBL-Plants: tr|O23960|O23960_SOYBN Acetyl-CoA carboxylase; Found in the gene: LotjaGi4g1v0439600 | 23 | ||
| – | Biotin carboxylase; TAIR: AT5G35360.1 acetyl Co-enzyme a carboxylase biotin carboxylase subunit; Swiss-Prot: sp|B9HBA8|ACCC1_POPTR Biotin carboxylase 1, chloroplastic; TrEMBL-Plants: tr|O23960|O23960_SOYBN Acetyl-CoA carboxylase; Found in the gene: LotjaGi4g1v0439600 | 23 | ||
| – | Succinate--CoA ligase [ADP]-forming] subunit beta; TAIR: AT2G20420.1 ATP citrate lyase (ACL) family protein; Swiss-Prot: sp|O82662|SUCB_ARATH Succinate--CoA ligase [ADP]-forming] subunit beta, mitochondrial; TrEMBL-Plants: tr|A5HIG2|A5HIG2_9FABA Succinate-CoA ligase subunit beta; Found in the gene: LotjaGi5g1v0154600 | 21 | ||
| – | Acetyl-CoA carboxylase, putative; TAIR: AT1G03090.2 methylcrotonyl-CoA carboxylase alpha chain; Swiss-Prot: sp|Q42777|MCCA_SOYBN Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; TrEMBL-Plants: tr|A0A151QXF8|A0A151QXF8_CAJCA Uncharacterized protein; Found in the gene: LotjaGi5g1v0170200 | 30 | ||
| – | Formate-dependent phosphoribosylglycinamide formyltransferase; TAIR: AT2G37690.1 phosphoribosylaminoimidazole carboxylase, putative / AIR carboxylase; Swiss-Prot: sp|P55195|PUR6_VIGAC Phosphoribosylaminoimidazole carboxylase, chloroplastic; TrEMBL-Plants: tr|K7LJS8|K7LJS8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0211000 | 32 | ||
| – | Phosphoribosylamine-glycine ligase; TAIR: AT1G09830.1 Glycinamide ribonucleotide (GAR) synthetase; Swiss-Prot: sp|P52420|PUR2_ARATH Phosphoribosylamine--glycine ligase, chloroplastic; TrEMBL-Plants: tr|K7LJM6|K7LJM6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0354900 | 28 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00877 | TIGRFAM | 1 | 4.00 |