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IPR007109 is a Brix domain.
<p>Analysis of the Brix (biogenesis of ribosomes in Xenopus) protein leaded to the identification of a region of 150-180 residues length, called the Brix domain, which is found in six protein families: one archaean family (I) including hypothetical proteins (one per genome); and five eukaryote families, each named according to a representative member and including close homologues of this prototype: (II) Peter Pan (D. melanogaster) and SSF1/2 (S.cerevisiae); (III) RPF1 (S. cerevisiae); (IV) IMP4 (S. cerevisiae); (V) Brix (X.laevis) and BRX1 (S. cerevisiae); and (VI) RPF2 (S.cerevisiae).</p> <p>Typically, a protein sequence belonging to the Brix domain superfamily contains a highly charged N-terminal segment (about 50 residues) followed by a single copy of the Brix domain and another highly charged C-terminal region (about 100 residues). The archaean sequences have two unique characteristics: (1) the charged regions are totally absent at the N terminus and are reduced in number to about 10 residues at the C terminus; and (2) the C-terminal part of the Brix domain itself is minimal. Two eukaryote groups have large insertions within the C-terminal region: about 70 residues in the group III and about 120 in the group II. Biological data for some proteins in this family suggest a role in ribosome biogenesis and rRNA binding [[cite:PUB00018304], [cite:PUB00018305], [cite:PUB00095726], [cite:PUB00060567]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: U3 small nucleolar ribonucleoprotein protein IMP4-like [Cicer arietinum] gi|502127749|ref|XP_004499820.1| | 9 | ||
| – | Ribosome biogenesis protein BRX1-like protein [Medicago truncatula] gi|357506041|ref|XP_003623309.1| | 9 | ||
| – | PREDICTED: ribosome biogenesis protein BRX1 homolog [Cicer arietinum] gi|502125035|ref|XP_004498770.1| | 9 | ||
| – | Ribosome production factor [Medicago truncatula] gi|358346575|ref|XP_003637342.1| | 8 | ||
| – | Ribosome production factor [Medicago truncatula] gi|358346575|ref|XP_003637342.1| | 10 | ||
| – | PREDICTED: peter Pan-like protein-like [Glycine max] gi|356544390|ref|XP_003540635.1| | 6 | ||
| – | PREDICTED: peter Pan-like protein-like [Glycine max] gi|356544390|ref|XP_003540635.1| | 6 | ||
| – | PREDICTED: ribosome production factor 2 homolog [Cicer arietinum] gi|502136609|ref|XP_004502751.1| | 8 | ||
| – | Ribosome biogenesis protein BRX1 like; TAIR: AT3G15460.1 Ribosomal RNA processing Brix domain protein; Swiss-Prot: sp|Q9LE16|BRX11_ARATH Ribosome biogenesis protein BRX1 homolog 1; TrEMBL-Plants: tr|I3SQI5|I3SQI5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0523100 | 9 | ||
| – | Ribosome biogenesis protein BRX1 like; TAIR: AT3G15460.1 Ribosomal RNA processing Brix domain protein; Swiss-Prot: sp|Q9LE16|BRX11_ARATH Ribosome biogenesis protein BRX1 homolog 1; TrEMBL-Plants: tr|I3SQI5|I3SQI5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0523100 | 9 | ||
| – | U3 small nucleolar ribonucleoprotein IMP4; TAIR: AT1G63780.1 Ribosomal RNA processing Brix domain protein; Swiss-Prot: sp|Q0VD01|IMP4_BOVIN U3 small nucleolar ribonucleoprotein protein IMP4; TrEMBL-Plants: tr|I1LLA9|I1LLA9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0113600 | 9 | ||
| – | Ribosome production factor 1; TAIR: AT4G01560.1 Ribosomal RNA processing Brix domain protein; Swiss-Prot: sp|Q5R631|RPF1_PONAB Ribosome production factor 1; TrEMBL-Plants: tr|A0A072TYA8|A0A072TYA8_MEDTR Ribosome production factor-like protein; Found in the gene: LotjaGi3g1v0405500 | 9 | ||
| – | Peter Pan-like protein; TAIR: AT5G61770.1 PETER PAN-like protein; Swiss-Prot: sp|Q9ASU7|PPAN_ARATH Peter Pan-like protein; TrEMBL-Plants: tr|A0A151TMY9|A0A151TMY9_CAJCA Peter Pan-like protein; Found in the gene: LotjaGi3g1v0528700 | 6 | ||
| – | Peter Pan-like protein; TAIR: AT5G61770.1 PETER PAN-like protein; Swiss-Prot: sp|Q9ASU7|PPAN_ARATH Peter Pan-like protein; TrEMBL-Plants: tr|I1LPJ3|I1LPJ3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0528700 | 7 | ||
| – | Peter Pan-like protein; TAIR: AT5G61770.1 PETER PAN-like protein; Swiss-Prot: sp|Q9ASU7|PPAN_ARATH Peter Pan-like protein; TrEMBL-Plants: tr|I1LPJ3|I1LPJ3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0528700 | 7 | ||
| – | Ribosome production factor 2 like; TAIR: AT3G23620.1 Ribosomal RNA processing Brix domain protein; Swiss-Prot: sp|Q9AWM9|RPF2_ORYSJ Ribosome production factor 2 homolog; TrEMBL-Plants: tr|A0A1J7IBE3|A0A1J7IBE3_LUPAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0091500 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 6.25 |