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IPR007248 is a Mpv17/PMP22.
<p>The 22kDa peroxisomal membrane protein (PMP22) is a major component of peroxisomal membranes. PMP22 seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the organelle membrane. PMP22 is synthesised on free cytosolic ribosomes and then directed to the peroxisome membrane by specific targeting information [[cite:PUB00009846]]. SYM1 in yeast and Mpv17 in higher eukaryotes are closely related peroxisomal proteins required to maintain mitochondrial DNA (mtDNA) integrity and stability [[cite:PUB00101095], [cite:PUB00015286]]. Mpv17 is involved in the development of early-onset glomerulosclerosis [[cite:PUB00009847]].</p> <p>Woronin sorting complex protein from Neurospora crassa is also included in this family. It is involved in both Woronin bodies (WB) formation and inherence [[cite:PUB00101094]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: PXMP2/4 family protein 4-like [Cicer arietinum] gi|502093311|ref|XP_004489899.1| | 10 | ||
| – | Protein Mpv17 [Medicago truncatula] gi|357474433|ref|XP_003607501.1| | 8 | ||
| – | PREDICTED: peroxisomal membrane protein PMP22-like [Cicer arietinum] gi|502116258|ref|XP_004495354.1| | 8 | ||
| – | PREDICTED: protein sym-1-like [Cicer arietinum] gi|502107584|ref|XP_004493310.1| | 7 | ||
| – | Peroxisomal membrane Mpv17/PMP22 family protein [Arabidopsis thaliana] gi|30695366|ref|NP_564615.3| | 5 | ||
| – | PREDICTED: protein SYM1-like isoform X2 [Cicer arietinum] gi|502082915|ref|XP_004487311.1| | 8 | ||
| – | PREDICTED: PXMP2/4 family protein 2-like [Cicer arietinum] gi|502124459|ref|XP_004498538.1| | 8 | ||
| – | PREDICTED: protein sym-1-like [Glycine max] gi|356549797|ref|XP_003543277.1| | 7 | ||
| – | PREDICTED: PXMP2/4 family protein 4-like [Cicer arietinum] gi|502120220|ref|XP_004496888.1| | 8 | ||
| – | PREDICTED: peroxisomal membrane protein PMP22-like [Cicer arietinum] gi|502079160|ref|XP_004486173.1| | 8 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT3G24570.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q54XX9|PX24B_DICDI PXMP2/4 family protein 2; TrEMBL-Plants: tr|I3SSU2|I3SSU2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0226100 | 8 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT3G24570.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q54XX9|PX24B_DICDI PXMP2/4 family protein 2; TrEMBL-Plants: tr|I3SSU2|I3SSU2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0226100 | 8 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT3G24570.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q54XX9|PX24B_DICDI PXMP2/4 family protein 2; TrEMBL-Plants: tr|I3SSU2|I3SSU2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0226100 | 8 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT3G24570.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q54XX9|PX24B_DICDI PXMP2/4 family protein 2; TrEMBL-Plants: tr|I3SSU2|I3SSU2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0226100 | 8 | ||
| – | Peroxisomal membrane MPV17/PMP22-like protein; TAIR: AT5G19750.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q7SCY7|SYM1_NEUCR Protein sym-1; TrEMBL-Plants: tr|A0A151TAQ5|A0A151TAQ5_CAJCA Protein sym-1; Found in the gene: LotjaGi1g1v0656600 | 8 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT5G43140.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q54FR4|PX24D_DICDI PXMP2/4 family protein 4; TrEMBL-Plants: tr|I3SB40|I3SB40_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0099700 | 10 | ||
| – | Peroxisomal membrane (Mpv17/PMP22) family protein; TAIR: AT1G52870.2 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q2KIY1|PXMP2_BOVIN Peroxisomal membrane protein 2; TrEMBL-Plants: tr|I1LUX5|I1LUX5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0077400 | 5 | ||
| – | Peroxisomal membrane (Mpv17/PMP22) family protein; TAIR: AT4G03410.2 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q754F0|SYM1_ASHGO Protein SYM1; TrEMBL-Plants: tr|A0A072VBB5|A0A072VBB5_MEDTR Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Found in the gene: LotjaGi3g1v0442100 | 11 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT2G42770.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q5TZ51|MPV17_DANRE Protein Mpv17; TrEMBL-Plants: tr|G7JTW9|G7JTW9_MEDTR Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Found in the gene: LotjaGi3g1v0451400 | 8 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT3G24570.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q4IPX8|SYM1_GIBZE Protein SYM1; TrEMBL-Plants: tr|A0A0B2SAA1|A0A0B2SAA1_GLYSO Protein sym-1; Found in the gene: LotjaGi4g1v0449100 | 8 | ||
| – | Peroxisomal membrane protein PMP22; TAIR: AT4G14305.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q9ZS51|PMP22_ARATH Peroxisomal membrane protein PMP22; TrEMBL-Plants: tr|I3SAV9|I3SAV9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0188300 | 8 | ||
| – | Peroxisomal membrane protein PMP22; TAIR: AT4G14305.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q9ZS51|PMP22_ARATH Peroxisomal membrane protein PMP22; TrEMBL-Plants: tr|I3SAV9|I3SAV9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0188300 | 8 | ||
| – | Peroxisomal membrane protein PMP22; TAIR: AT4G14305.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q9ZS51|PMP22_ARATH Peroxisomal membrane protein PMP22; TrEMBL-Plants: tr|I3SAV9|I3SAV9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0188300 | 8 | ||
| – | Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; TAIR: AT4G33905.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q54FR4|PX24D_DICDI PXMP2/4 family protein 4; TrEMBL-Plants: tr|I1LEF9|I1LEF9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0323800 | 7 | ||
| – | Peroxisomal membrane MPV17/PMP22-like protein; TAIR: AT4G04470.1 Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein; Swiss-Prot: sp|Q9ZS51|PMP22_ARATH Peroxisomal membrane protein PMP22; TrEMBL-Plants: tr|A0A151T6U9|A0A151T6U9_CAJCA Peroxisomal membrane protein PMP22; Found in the gene: LotjaGi6g1v0292800 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 4.00 |