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IPR007274 is a Ctr copper transporter.
<p>This entry represents the high-affinity copper transporter Ctr1 proteins. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high-affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane [[cite:PUB00093980]]. A series of clustered methionine residues in the hydrophilic extracellular domain, and an MXXXM motif in the second transmembrane domain, are important for copper uptake. These methionines probably coordinate copper during the process of metal transport [[cite:PUB00019362]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Copper ion transmembrane transporter activity | Enables the transfer of copper (Cu) ions from one side of a membrane to the other. | ||
| Cellular component | Integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | ||
| Biological process | Copper ion transmembrane transport | The directed movement of copper cation across a membrane. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: copper transporter 6-like isoform 1 [Glycine max] gi|356496102|ref|XP_003516909.1| | 8 | ||
| – | PREDICTED: copper transporter 5.1-like [Cicer arietinum] gi|502132564|ref|XP_004501422.1| | 8 | ||
| – | 7 | |||
| – | PREDICTED: copper transporter 1-like [Glycine max] gi|356566608|ref|XP_003551522.1| | 8 | ||
| – | PREDICTED: copper transporter 2-like [Cicer arietinum] gi|502148393|ref|XP_004507149.1| | 8 | ||
| – | PREDICTED: copper transporter 5-like [Cicer arietinum] gi|502125193|ref|XP_004498836.1| | 9 | ||
| – | Copper transporter; TAIR: AT5G20650.1 copper transporter 5; Swiss-Prot: sp|Q93VM8|COPT5_ARATH Copper transporter 5; TrEMBL-Plants: tr|I3S402|I3S402_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0372000 | 8 | ||
| – | Copper transporter; TAIR: AT5G20650.1 copper transporter 5; Swiss-Prot: sp|Q93VM8|COPT5_ARATH Copper transporter 5; TrEMBL-Plants: tr|I3S402|I3S402_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0372000 | 8 | ||
| – | Copper transporter, putative; TAIR: AT2G26975.1 Ctr copper transporter family; Swiss-Prot: sp|Q8GWP3|COPT6_ARATH Copper transporter 6; TrEMBL-Plants: tr|I3T3C3|I3T3C3_MEDTR Ctr family copper transporter; Found in the gene: LotjaGi1g1v0575200 | 9 | ||
| – | Copper transporter, putative; TAIR: AT5G59030.1 copper transporter 1; Swiss-Prot: sp|Q39065|COPT1_ARATH Copper transporter 1; TrEMBL-Plants: tr|A0A151R1R4|A0A151R1R4_CAJCA Copper transporter 1; Found in the gene: LotjaGi1g1v0575200 | 8 | ||
| – | Copper transporter family protein; TAIR: AT2G26975.1 Ctr copper transporter family; Swiss-Prot: sp|Q8GWP3|COPT6_ARATH Copper transporter 6; TrEMBL-Plants: tr|A0A072UWE8|A0A072UWE8_MEDTR Ctr family copper transporter; Found in the gene: LotjaGi3g1v0491700 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 9.09 |