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IPR009097 is a Cyclic phosphodiesterase.
<p>This entry represents a β-barrel domain consisting of a duplication of a β/α/β/α/β motif, which is found in plant cyclic phosphodiesterases (CPDases) [[cite:PUB00013260]], as well as catalytic domains from mammalian 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) [[cite:PUB00036006]], and bacterial and archaeal LigT-like 2',3'-cyclic phosphodiesterases (originally identified as 2'-5' RNA ligases) [[cite:PUB00075358]]. This β-barrel domain is similar in structure to the β-barrel found in prokaryotic DNA topoisomerases I and III.</p> <p>The catalytic domain of CNPase from animals catalyses the hydrolysis of nucleoside 2',3'-cyclic monophosphates to nucleoside 2'-monophosphates [[cite:PUB00083499]]. The archaeobacterial LigT-like enzymes hydrolyze 2',3'-cyclic phosphate in (oligo)nucleotides and join the produced 2'-phosphate to a 5'-hydroxyl group of another (oligo)nucleotide to form atypical 2',5'-linkages. Such activity has not been reported for CNPase [[cite:PUB00083500]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: UPF0406 protein C16orf57-like isoform 1 [Glycine max] gi|356495919|ref|XP_003516818.1| | 7 | ||
| – | RNA ligase/cyclic nucleotide phosphodiesterase family protein isoform 1 [Theobroma cacao] gi|508710415|gb|EOY02312.1| | 6 | ||
| – | Activating signal cointegrator 1 complex subunit [Medicago truncatula] gi|357454839|ref|XP_003597700.1| | 15 | ||
| – | Cyclic phosphodiesterase [Medicago truncatula] gi|357519169|ref|XP_003629873.1| | 8 | ||
| – | RNA ligase/cyclic nucleotide phosphodiesterase; TAIR: AT5G40190.1 RNA ligase/cyclic nucleotide phosphodiesterase family protein; Swiss-Prot: sp|A7GMB9|Y945_BACCN Putative phosphoesterase Bcer98_0945; TrEMBL-Plants: tr|I3S8C4|I3S8C4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0249600 | 6 | ||
| – | RNA ligase/cyclic nucleotide phosphodiesterase family protein; TAIR: AT4G18930.1 RNA ligase/cyclic nucleotide phosphodiesterase family protein; Swiss-Prot: sp|O04147|CPD_ARATH Cyclic phosphodiesterase; TrEMBL-Plants: tr|G7L7Z2|G7L7Z2_MEDTR Cyclic phosphodiesterase-like protein; Found in the gene: LotjaGi4g1v0381800 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF55144 | SUPERFAMILY | 1 | 16.67 |