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IPR010674

Source: InterPro

Description

IPR010674 is a Nucleolar GTP-binding protein 1, Rossman-fold domain.

<p>This domain represents a conserved region of approximately 60 residues in length within nucleolar GTP-binding protein 1 (NOG1). The NOG1 family includes eukaryotic, bacterial and archaeal proteins. In Saccharomyces cerevisiae, the NOG1 gene has been shown to be essential for cell viability, suggesting that NOG1 may play an important role in nucleolar functions. In particular, NOG1 is believed to be functionally linked to ribosome biogenesis, which occurs in the nucleolus. In eukaryotes, NOG1 mutants were found to disrupt the biogenesis of the 60S ribosomal subunit [[cite:PUB00014934]].</p> <p>The DRG and OBG proteins as well as the prokaryotic NOG-like proteins are homologous throughout their length to the amino half of eukaryotic NOG1, which contains the GTP binding motifs ([interpro:IPR006073]); the N-terminal GTP-binding motif is required for function.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005525
Molecular function GTP binding Interacting selectively and non-covalently with GTP, guanosine triphosphate.
Subterm of

Associated Lotus transcripts 12

Transcript Name Description Predicted domains Domain count
Lj1g3v3608420.1
– PREDICTED: nucleolar GTP-binding protein 1-like [Glycine max] gi|356527250|ref|XP_003532225.1|
Domains
13
Lj1g3v3608420.2
– PREDICTED: nucleolar GTP-binding protein 1-like [Glycine max] gi|356527250|ref|XP_003532225.1|
Domains
14
Lj2g3v1645560.1
– PREDICTED: nucleolar GTP-binding protein 1-like [Glycine max] gi|356538952|ref|XP_003537964.1|
Domains
18
Lj4g3v1327810.1
– PREDICTED: nucleolar GTP-binding protein 1-like [Glycine max] gi|356538952|ref|XP_003537964.1|
Domains
16
LotjaGi1g1v0597800.1
– Nucleolar GTP-binding protein 1; TAIR: AT1G80770.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q6FRV0|NOG1_CANGA Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|K7LAJ8|K7LAJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0597800
Domains
17
LotjaGi2g1v0356500.1
– Nucleolar GTP-binding protein 1; TAIR: AT1G50920.1 Nucleolar GTP-binding protein; Swiss-Prot: sp|Q9C6I8|NOG1_ARATH Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|A0A0B2R041|A0A0B2R041_GLYSO Nucleolar GTP-binding protein 1; Found in the gene: LotjaGi2g1v0356500
Domains
21
LotjaGi2g1v0356500.2
– Nucleolar GTP-binding protein 1; TAIR: AT1G50920.1 Nucleolar GTP-binding protein; Swiss-Prot: sp|Q9C6I8|NOG1_ARATH Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|A0A0B2R041|A0A0B2R041_GLYSO Nucleolar GTP-binding protein 1; Found in the gene: LotjaGi2g1v0356500
Domains
21
LotjaGi2g1v0356500.3
– Nucleolar GTP-binding protein 1; TAIR: AT1G50920.1 Nucleolar GTP-binding protein; Swiss-Prot: sp|Q9C6I8|NOG1_ARATH Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|A0A0B2R041|A0A0B2R041_GLYSO Nucleolar GTP-binding protein 1; Found in the gene: LotjaGi2g1v0356500
Domains
21
LotjaGi4g1v0218400.1
– Nucleolar GTP-binding protein 1; TAIR: AT1G50920.1 Nucleolar GTP-binding protein; Swiss-Prot: sp|Q9C6I8|NOG1_ARATH Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|A0A0B2R041|A0A0B2R041_GLYSO Nucleolar GTP-binding protein 1; Found in the gene: LotjaGi4g1v0218400
Domains
21
LotjaGi4g1v0218400.2
– Nucleolar GTP-binding protein 1; TAIR: AT1G50920.1 Nucleolar GTP-binding protein; Swiss-Prot: sp|Q9C6I8|NOG1_ARATH Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|A0A0B2R041|A0A0B2R041_GLYSO Nucleolar GTP-binding protein 1; Found in the gene: LotjaGi4g1v0218400
Domains
21
LotjaGi4g1v0218400.3
– Nucleolar GTP-binding protein 1; TAIR: AT1G50920.1 Nucleolar GTP-binding protein; Swiss-Prot: sp|Q9C6I8|NOG1_ARATH Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|A0A0B2R041|A0A0B2R041_GLYSO Nucleolar GTP-binding protein 1; Found in the gene: LotjaGi4g1v0218400
Domains
21
LotjaGi4g1v0218400.4
– Nucleolar GTP-binding protein 1; TAIR: AT1G50920.1 Nucleolar GTP-binding protein; Swiss-Prot: sp|Q9C6I8|NOG1_ARATH Nucleolar GTP-binding protein 1; TrEMBL-Plants: tr|A0A0B2R041|A0A0B2R041_GLYSO Nucleolar GTP-binding protein 1; Found in the gene: LotjaGi4g1v0218400
Domains
21

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 8.33