Domain Predictions — View

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IPR012137

Source: InterPro

Description

IPR012137 is a Nitrate reductase NADH dependent.

<p>This entry represents the NADH dependent nitrate reductase (NR) from plants and fungi, including NIA1 and NIA2 from Arabidopsis. They contain an N-terminal oxidoreductase molybdopterin binding domain and a C-terminal FAD-binding domain. In Arabidopsis, NR-mediated nitric oxide (NO) synthesis is required for ABA-induced stomatal closure [[cite:PUB00074254]]. AtNIA1 is involved in the first step of nitrate assimilation [[cite:PUB00074255], [cite:PUB00074253]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0006809 View details of GO:0006809 AmiGO InterPro QuickGO	Biological process	Nitric oxide biosynthetic process	The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	Subterm of GO:0042136 GO:0044271 GO:0046209 GO:1903409
GO:0042128 View details of GO:0042128 AmiGO InterPro QuickGO	Biological process	Nitrate assimilation	The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.	Subterm of GO:0042126 GO:0071941
GO:0050464 View details of GO:0050464 AmiGO InterPro QuickGO	Molecular function	Nitrate reductase (NADPH) activity	Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.	Subterm of GO:0008940 GO:0046857

Associated Lotus transcripts 2

Transcript	Name	Description	Predicted domains	Domain count
Lj0g3v0006719.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	RecName: Full=Nitrate reductase [NADH] gi\|730146\|sp\|P39869.1\|NIA_LOTJA	Domains G3DSA:2.40.30.10 G3DSA:2.60.40.650 G3DSA:3.10.120.10 G3DSA:3.40.50.80 G3DSA:3.90.420.10 IPR000572 IPR001199 IPR001433 IPR001709 IPR001834 IPR005066 IPR008333 IPR008335 IPR012137 IPR014756 IPR017927 IPR017938 IPR018506 IPR022407 PF00173 PF00174 PF00175 PF00970 PF03404 PIRSF000233 PR00363 PR00371 PR00406 PR00407 PS00191 PS00559 PS50255 PS51384 PTHR19370 PTHR19370:SF100 SM01117 SSF52343 SSF55856 SSF56524 SSF63380 SSF81296 cd02112 cd06183	43
LotjaGi1g1v0152000.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Nitrate reductase; TAIR: AT1G77760.1 nitrate reductase 1; Swiss-Prot: sp\|P39869\|NIA_LOTJA Nitrate reductase [NADH]; TrEMBL-Plants: tr\|E7ELN7\|E7ELN7_MEDTR Nitrate reductase; Found in the gene: LotjaGi1g1v0152000	Domains G3DSA:2.40.30.10 G3DSA:2.60.40.650 G3DSA:3.10.120.10 G3DSA:3.40.50.80 G3DSA:3.90.420.10 IPR000572 IPR001199 IPR001433 IPR001709 IPR001834 IPR005066 IPR008333 IPR008335 IPR012137 IPR014756 IPR017927 IPR017938 IPR018506 IPR022407 IPR036374 IPR036400 IPR039261 PF00173 PF00174 PF00175 PF00970 PF03404 PIRSF000233 PR00363 PR00371 PR00406 PR00407 PS00191 PS00559 PS50255 PS51384 PTHR19370 PTHR19370:SF195 SM01117 SSF52343 SSF55856 SSF56524 SSF63380 SSF81296 cd02112 cd06183	46

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
cd06183	CDD	1	50.00