Description

IPR036374 is a Oxidoreductase, molybdopterin-binding domain superfamily.

<p>A number of different eukaryotic oxidoreductases that require and bind a molybdopterin cofactor have been shown [[cite:PUB00000608]] to share a few regions of sequence similarity. These enzymes include xanthine dehydrogenase ([ec:1.1.1.204]), aldehyde oxidase ([ec:1.2.3.1]), nitrate reductase ([ec:1.7.1.1]), and sulphite oxidase ([ec:1.8.3.1]). The multidomain redox enzyme NAD(P)H:nitrate reductase (NR) catalyses the reduction of nitrate to nitrite in a single polypeptide electron transport chain with electron flow from NAD(P)H-FAD-cytochrome b5-molybdopterin-NO(3). Three forms of NR are known, an NADH-specific enzyme found in higher plants and algae ([ec:1.7.1.1]); an NAD(P)H-bispecific enzyme found in higher plants, algae and fungi ([ec:1.7.1.2]); and an NADPH-specific enzyme found only in fungi ([ec:1.7.1.3]) [[cite:PUB00005356]]. The mitochondrial enzyme sulphite oxidase (sulphite:ferricytochrome c oxidoreductase; [ec:1.8.2.1]) catalyses oxidation of sulphite to sulphate, using cytochrome c as the physiological electron acceptor. Sulphite oxidase consists of two structure/function domains, an N-terminal haem domain, similar to cytochrome b5; and a C-terminal molybdopterin domain [[cite:PUB00007725]].</p> <p>This domain contains a three layers β-sheet structure and a β-grasp like motif.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 7

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: