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IPR015760 is a Translation initiation factor IF- 2.
<p>Initiation factor 2 (IF-2) is one of the three factors required for the initiation of protein biosynthesis in bacteria [[cite:PUB00085958]]. IF-2 promotes the GTP-dependent binding of the initiator tRNA to the small subunit of the ribosome. IF-2 is a protein of about 70 to 95kDa that contains a central GTP-binding domain flanked by a highly variable N-terminal domain and a more conserved C-terminal domain. Some members of this group undergo protein self splicing that involves a post-translational excision of the intein followed by peptide ligation.</p> <p>The function of IF-2 in facilitating the proper binding of initiator methionyl-tRNA to the ribosomal P site appears to be universally conserved [[cite:PUB00035262]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Translation initiation factor IF-2; TAIR: AT4G11160.1 Translation initiation factor 2, small GTP-binding protein; Swiss-Prot: sp|B8EIA7|IF2_METSB Translation initiation factor IF-2; TrEMBL-Plants: tr|V7D180|V7D180_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0752600 | 30 | ||
| – | Translation initiation factor IF-2; TAIR: AT4G11160.1 Translation initiation factor 2, small GTP-binding protein; Swiss-Prot: sp|Q5FQM3|IF2_GLUOX Translation initiation factor IF-2; TrEMBL-Plants: tr|I1NBL5|I1NBL5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0752600 | 25 | ||
| – | Translation initiation factor IF-2; TAIR: AT4G11160.1 Translation initiation factor 2, small GTP-binding protein; Swiss-Prot: sp|Q5FQM3|IF2_GLUOX Translation initiation factor IF-2; TrEMBL-Plants: tr|I1NBL5|I1NBL5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0752600 | 25 | ||
| – | Translation initiation factor IF-2; TAIR: AT4G11160.1 Translation initiation factor 2, small GTP-binding protein; Swiss-Prot: sp|Q5FQM3|IF2_GLUOX Translation initiation factor IF-2; TrEMBL-Plants: tr|I1NBL5|I1NBL5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0752600 | 25 | ||
| – | Translation initiation factor IF-2; TAIR: AT4G11160.1 Translation initiation factor 2, small GTP-binding protein; Swiss-Prot: sp|Q5FQM3|IF2_GLUOX Translation initiation factor IF-2; TrEMBL-Plants: tr|I1NBL5|I1NBL5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0752600 | 25 | ||
| – | Translation initiation factor IF-2; TAIR: AT1G17220.1 Translation initiation factor 2, small GTP-binding protein; Swiss-Prot: sp|P57997|IF2C_PHAVU Translation initiation factor IF-2, chloroplastic; TrEMBL-Plants: tr|V7BXF4|V7BXF4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0142900 | 29 | ||
| – | Translation initiation factor IF-2; TAIR: AT1G17220.1 Translation initiation factor 2, small GTP-binding protein; Swiss-Prot: sp|P57997|IF2C_PHAVU Translation initiation factor IF-2, chloroplastic; TrEMBL-Plants: tr|V7BXF4|V7BXF4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0142900 | 29 | ||
| – | Translation initiation factor if-2, putative; TAIR: AT1G76810.1 eukaryotic translation initiation factor 2 (eIF-2) family protein; Swiss-Prot: sp|Q10251|IF2P_SCHPO Eukaryotic translation initiation factor 5B; TrEMBL-Plants: tr|V7BF46|V7BF46_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0291500 | 27 | ||
| – | Translation initiation factor if-2, putative; TAIR: AT1G76810.1 eukaryotic translation initiation factor 2 (eIF-2) family protein; Swiss-Prot: sp|Q10251|IF2P_SCHPO Eukaryotic translation initiation factor 5B; TrEMBL-Plants: tr|V7BF46|V7BF46_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0291500 | 27 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 11.11 |