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IPR016363

Description

IPR016363 is a Legume lectin.

<p>This group represents L-type lectins from plants, including leukoagglutinins which bind sialic acid [[cite:PUB00083239]].</p> <p>Lectins are carbohydrate-binding proteins. Leguminous lectins form one of the largest lectin families and resemble each other in their physicochemical properties, though they differ in their carbohydrate specificities. They bind either glucose/mannose or galactose [[cite:PUB00001507]]. Carbohydrate-binding activity depends on the simultaneous presence of both a calcium and a transition metal ion [[cite:PUB00046607]]. The exact function of legume lectins is not known, but they may be involved in the attachment of nitrogen-fixing bacteria to legumes and in the protection against pathogens [[cite:PUB00057387], [cite:PUB00057388]].</p> <p>Some legume lectins are proteolytically processed to produce two chains, beta (which corresponds to the N-terminal) and alpha (C-terminal) [[cite:PUB00057390]]. The lectin concanavalin A (conA) from jack bean is exceptional in that the two chains are transposed and ligated (by formation of a new peptide bond). The N terminus of mature conA thus corresponds to that of the alpha chain and the C terminus to the beta chain [[cite:PUB00057389]]. Though the legume lectins monomer is structurally well conserved, their quaternary structures vary widely [[cite:PUB00046607]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Carbohydrate binding Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.

Associated Lotus transcripts 21

Transcript Name Description Predicted domains Domain count
Chain A, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404520|pdb|2EIG|B Chain B, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404521|pdb|2EIG|C Chain C, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404522|pdb|2EIG|D Chain D, Lotus Tetragonolobus Seed Lectin (Isoform)] gi|169404519|pdb|2EIG|A 19
Lectin [Robinia pseudoacacia] gi|4115547|dbj|BAA36415.1| 21
Lectin-related polypeptide [Robinia pseudoacacia] gi|4115549|dbj|BAA36416.1| 14
Chain A, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404520|pdb|2EIG|B Chain B, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404521|pdb|2EIG|C Chain C, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404522|pdb|2EIG|D Chain D, Lotus Tetragonolobus Seed Lectin (Isoform)] gi|169404519|pdb|2EIG|A 18
RecName: Full=Seed lectin; AltName: Full=LECSJASG; Flags: Precursorgi|1755064|gb|AAB51441.1| lectin precursor [Sophora japonica] gi|3122340|sp|P93535.1|LECS_SOPJA 20
Lectin protein, partial [Sophora japonica] gi|431837890|gb|AGA94529.1| 14
PREDICTED: agglutinin-2-like [Cicer arietinum] gi|502154472|ref|XP_004509711.1| 22
PREDICTED: agglutinin-2-like [Cicer arietinum] gi|502154472|ref|XP_004509711.1| 21
Lectin protein, partial [Sophora japonica] gi|431837890|gb|AGA94529.1| 20
Chain A, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404520|pdb|2EIG|B Chain B, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404521|pdb|2EIG|C Chain C, Lotus Tetragonolobus Seed Lectin (Isoform)gi|169404522|pdb|2EIG|D Chain D, Lotus Tetragonolobus Seed Lectin (Isoform)] gi|169404519|pdb|2EIG|A 18
Lectin; TAIR: AT5G65600.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|P93535|LECS_STYJP Seed lectin; TrEMBL-Plants: tr|I3SRF2|I3SRF2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0376900 20
Lectin; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|Q39527|LECR_CLAKE Lectin-related protein; TrEMBL-Plants: tr|I3SCP3|I3SCP3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0377000 21
Lectin; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|Q41161|LCS2_ROBPS Seed agglutinin 2; TrEMBL-Plants: tr|L0H879|L0H879_STYJP Lectin protein; Found in the gene: LotjaGi1g1v0377100 14
Lectin; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|P19664|LEC_LOTTE Anti-H(O) lectin; TrEMBL-Plants: tr|I3SL71|I3SL71_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0157900 19
Lectin; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|P19664|LEC_LOTTE Anti-H(O) lectin; TrEMBL-Plants: tr|D0VWW1|D0VWW1_LOTTE Lectin; Found in the gene: LotjaGi2g1v0158100 12
Lectin-like protein; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|Q39529|LEC2_CLAKE Agglutinin-2; TrEMBL-Plants: tr|K7L993|K7L993_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0329800 22
Lectin; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|Q39529|LEC2_CLAKE Agglutinin-2; TrEMBL-Plants: tr|K7LF03|K7LF03_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0329900_LC 20
Lectin-like protein; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|Q39529|LEC2_CLAKE Agglutinin-2; TrEMBL-Plants: tr|K7K1C5|K7K1C5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0330000 20
Lectin protein; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|Q41161|LCS2_ROBPS Seed agglutinin 2; TrEMBL-Plants: tr|L0H879|L0H879_STYJP Lectin protein; Found in the gene: LotjaGi3g1v0029600 20
Lectin; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|Q41160|LCB3_ROBPS Putative bark agglutinin LECRPA3; TrEMBL-Plants: tr|I3SK58|I3SK58_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0257900 14
Lectin; TAIR: AT5G10530.1 Concanavalin A-like lectin protein kinase family protein; Swiss-Prot: sp|P19664|LEC_LOTTE Anti-H(O) lectin; TrEMBL-Plants: tr|D0VWW1|D0VWW1_LOTTE Lectin; Found in the gene: LotjaGi5g1v0266100 18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd06899 CDD 1 4.76