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IPR019740

Source: InterPro

Description

IPR019740 is a Pyridoxamine 5'-phosphate oxidase, conserved site.

<p>Pyridoxamine 5'-phosphate oxidase ([ec:1.4.3.5]) is a FMN flavoprotein involved in the de novo synthesis of pyridoxine (vitamin B6) and pyridoxal phosphate. It oxidizes pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P. The sequences of the enzyme from bacterial (genes pdxH or fprA) [[cite:PUB00002199]] and fungal (gene PDX3) [[cite:PUB00002264]] sources show that this protein has been highly conserved throughout evolution. PdxH is evolutionary related to one of the enzymes in the phenazine biosynthesis protein pathway, phzD (also known as phzG) [[cite:PUB00001735]].</p> <p>This entry represents a highly conserved region located in the C-terminal part of these enzymes.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016638
Molecular function Oxidoreductase activity, acting on the CH-NH2 group of donors Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
Subterm of
GO:0055114
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
Subterm of

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj1g3v1615290.1
– PREDICTED: pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic-like [Cicer arietinum] gi|502132996|ref|XP_004501612.1|
Domains
22
Lj1g3v1615290.2
– PREDICTED: pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic-like [Cicer arietinum] gi|502132996|ref|XP_004501612.1|
Domains
28
LotjaGi1g1v0349900.1
– Pyridoxine/pyridoxamine 5'-phosphate oxidase; TAIR: AT5G49970.1 pyridoxin (pyrodoxamine) 5'-phosphate oxidase; Swiss-Prot: sp|Q9LTX3|PPOX1_ARATH Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic; TrEMBL-Plants: tr|I1JV54|I1JV54_SOYBN NAD(P)H-hydrate epimerase; Found in the gene: LotjaGi1g1v0349900
Domains
29

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00558 TIGRFAM 1 33.33