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IPR020624 is a Schiff base-forming aldolase, conserved site.
<p>This entry represents an conserved site found in members of a structural superfamily of Schiff base-forming aldolases that catalyse reactions in different biological pathways. This superfamily includes members such as dihydrodipicolinate synthase (DHDPS), N-acetylneuraminate lyase (NAL) and 2-keto-3-deoxygluconate aldolase (KDG aldolase) [[cite:PUB00072988]]. One of the Escherichia coli proteins containing this site, dapA ([swissprot:P0A6L2]), was first identified as dihydrodipicolinate synthase (DHDPS) [[cite:PUB00000520]]. Later, it has been identified as 4-hydroxy-tetrahydrodipicolinate synthases ([ec:4.3.3.7]) [[cite:PUB00072990]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Lyase activity | Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic-like [Cicer arietinum] gi|502104773|ref|XP_004492645.1| | 14 | ||
| – | PREDICTED: 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic-like [Cicer arietinum] gi|502157868|ref|XP_004510938.1| | 14 | ||
| – | 4-hydroxy-tetrahydrodipicolinate synthase; TAIR: AT2G45440.1 dihydrodipicolinate synthase; Swiss-Prot: sp|Q42800|DAPA_SOYBN 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic; TrEMBL-Plants: tr|I1L6T8|I1L6T8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0463600 | 17 | ||
| – | 4-hydroxy-tetrahydrodipicolinate synthase; TAIR: AT2G45440.1 dihydrodipicolinate synthase; Swiss-Prot: sp|Q42800|DAPA_SOYBN 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic; TrEMBL-Plants: tr|I1L6T8|I1L6T8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0463600 | 18 | ||
| – | 4-hydroxy-tetrahydrodipicolinate synthase; TAIR: AT3G60880.1 dihydrodipicolinate synthase 1; Swiss-Prot: sp|Q42800|DAPA_SOYBN 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic; TrEMBL-Plants: tr|G7L0A3|G7L0A3_MEDTR 4-hydroxy-tetrahydrodipicolinate synthase; Found in the gene: LotjaGi1g1v0463600 | 17 | ||
| – | 4-hydroxy-tetrahydrodipicolinate synthase; TAIR: AT2G45440.1 dihydrodipicolinate synthase; Swiss-Prot: sp|Q42948|DAPA_TOBAC 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic; TrEMBL-Plants: tr|A0A151TBN5|A0A151TBN5_CAJCA 4-hydroxy-tetrahydrodipicolinate synthase; Found in the gene: LotjaGi3g1v0431800 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00950 | CDD | 1 | 16.67 |