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IPR022003 is a RST domain.
<p>The RST (for RCD1 SRO TAF4) domain is a plant-specific domain found in WWE- PARPs (poly(ADP-ribose) polymerase) and TAF4s (TBP-Associated Factor 4), a component of several multimeric protein complexes including primarily the general transcription factor TFIID involved in transcriptional initiation. The RST domain is a protein-protein interaction domain suggested to be critical for the interaction with several, mostly plant-specific transcription factors [[cite:PUB00066838], [cite:PUB00053132]].</p> <p>The RST domain structure has a unique helical arrangement composed of four α helices flanked by disordered termini. The four-helix fold of the RST domain organizes in an open, hydrophobic L-shape with room for catching the ligand [[cite:PUB00094752]]. A strong conservation of a large number of aliphatic amino acids in the N- and C-termini of the RST domain, with a conserved tyrosine in the middle of the domain and two conserved positively charged amino acids in the second half of the domain, is striking [[cite:PUB00066838]]. This entry represents the RST domain.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356496243|ref|XP_003516978.1| | 6 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356496243|ref|XP_003516978.1| | 6 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356496243|ref|XP_003516978.1| | 8 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356496243|ref|XP_003516978.1| | 8 | ||
| – | PREDICTED: probable inactive poly [ADP]-ribose] gi|502133905|ref|XP_004501930.1| | 9 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356496243|ref|XP_003516978.1| | 5 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356531443|ref|XP_003534287.1| | 8 | ||
| – | PREDICTED: serine-rich adhesin for platelets-like [Cicer arietinum] gi|502162858|ref|XP_004512638.1| | 10 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|502092735|ref|XP_004489757.1| | 12 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356496243|ref|XP_003516978.1| | 11 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|502092735|ref|XP_004489757.1| | 4 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|356496243|ref|XP_003516978.1| | 8 | ||
| – | PREDICTED: probable inactive poly [ADP]-ribose] gi|502152314|ref|XP_004508868.1| | 12 | ||
| – | PREDICTED: probable inactive poly [ADP]-ribose] gi|502152314|ref|XP_004508868.1| | 9 | ||
| – | PREDICTED: inactive poly [ADP]-ribose] gi|460397706|ref|XP_004244408.1| | 4 | ||
| – | PREDICTED: serine-rich adhesin for platelets-like [Cicer arietinum] gi|502162858|ref|XP_004512638.1| | 11 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G23550.1 similar to RCD one 2; Swiss-Prot: sp|Q9ZUD9|SRO2_ARATH Probable inactive poly [ADP]-ribose] polymerase SRO2; TrEMBL-Plants: tr|V7AXP9|V7AXP9_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0180200 | 9 | ||
| – | Transcription initiation factor TFIID subunit 4; TAIR: AT5G43130.1 TBP-associated factor 4; Swiss-Prot: sp|F4K4L7|TAF4B_ARATH Transcription initiation factor TFIID subunit 4b; TrEMBL-Plants: tr|I1K853|I1K853_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0360700 | 9 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G32230.1 WWE protein-protein interaction domain protein family; Swiss-Prot: sp|Q8RY59|RCD1_ARATH Inactive poly [ADP]-ribose] polymerase RCD1; TrEMBL-Plants: tr|W9RNQ8|W9RNQ8_9ROSA Putative inactive poly [ADP]-ribose] polymerase SRO1; Found in the gene: LotjaGi1g1v0411100 | 10 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G32230.2 WWE protein-protein interaction domain protein family; Swiss-Prot: sp|Q8RY59|RCD1_ARATH Inactive poly [ADP]-ribose] polymerase RCD1; TrEMBL-Plants: tr|A0A072VQR8|A0A072VQR8_MEDTR Inactive poly [ADP]-ribose] polymerase RCD1; Found in the gene: LotjaGi2g1v0327000 | 13 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G32230.1 WWE protein-protein interaction domain protein family; Swiss-Prot: sp|Q8RY59|RCD1_ARATH Inactive poly [ADP]-ribose] polymerase RCD1; TrEMBL-Plants: tr|I1J4R8|I1J4R8_SOYBN Radical-induced cell death protein; Found in the gene: LotjaGi2g1v0336000 | 9 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G32230.2 WWE protein-protein interaction domain protein family; Swiss-Prot: sp|Q8RY59|RCD1_ARATH Inactive poly [ADP]-ribose] polymerase RCD1; TrEMBL-Plants: tr|V7CJA3|V7CJA3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi3g1v0022500_LC | 9 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G32230.1 WWE protein-protein interaction domain protein family; Swiss-Prot: sp|Q8RY59|RCD1_ARATH Inactive poly [ADP]-ribose] polymerase RCD1; TrEMBL-Plants: tr|V7CJA3|V7CJA3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0118200_LC | 5 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G23550.1 similar to RCD one 2; Swiss-Prot: sp|Q9ZUD9|SRO2_ARATH Probable inactive poly [ADP]-ribose] polymerase SRO2; TrEMBL-Plants: tr|A0A072US10|A0A072US10_MEDTR Inactive poly [ADP]-ribose] polymerase SRO4; Found in the gene: LotjaGi4g1v0233600 | 9 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT5G62520.1 similar to RCD one 5; Swiss-Prot: sp|Q9FJJ3|SRO5_ARATH Probable inactive poly [ADP]-ribose] polymerase SRO5; TrEMBL-Plants: tr|I1MTH3|I1MTH3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0233600 | 10 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT1G32230.2 WWE protein-protein interaction domain protein family; Swiss-Prot: sp|Q8RY59|RCD1_ARATH Inactive poly [ADP]-ribose] polymerase RCD1; TrEMBL-Plants: tr|V7CJA3|V7CJA3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0285000_LC | 9 | ||
| – | Transcription initiation factor TFIID subunit 4; TAIR: AT5G43130.1 TBP-associated factor 4; Swiss-Prot: sp|F4K4L7|TAF4B_ARATH Transcription initiation factor TFIID subunit 4b; TrEMBL-Plants: tr|K7MNL8|K7MNL8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0032300 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 3.70 |