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IPR024435 is a Histidyl tRNA synthetase-related domain.
<p>This entry represents the histidyl-tRNA synthetase-related (HisRS-related) domain, found largely in Gcn2 protein kinases [[cite:PUB00056048]]. In yeast, Gcn2 phosphorylates the alpha subunit of eukaryotic initiation factor-2 (eIF-2) when the cells face the starvation for amino acids. The HisRS-related domain is required for activation of Gcn2 kinase function [[cite:PUB00063768], [cite:PUB00062021]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Protein kinase family protein; TAIR: AT3G59410.4 protein kinase family protein; Swiss-Prot: sp|Q9LX30|GCN2_ARATH eIF-2-alpha kinase GCN2; TrEMBL-Plants: tr|A0A151RUS1|A0A151RUS1_CAJCA Putative serine/threonine-protein kinase GCN2; Found in the gene: LotjaGi3g1v0498400 | 32 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |