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IPR006575 is a RWD domain.
<p>The RWD domain is a conserved region of about 110 amino acid residues, which has been identified in the mouse GCN2 eIF2alpha kinase and histidyl-tRNA synthetase and in presumed orthologues in other eukaryotic species from yeast to vertebrates. Additionally, it is also found in WD repeat containing proteins, yeast DEAD (DEXD)-like helicases, many RING-finger containing proteins, the UPF0029 uncharacterised protein family and a range of hypothetical proteins. The RWD domain has been named after the better characterised RING finger and WD repeat containing proteins and DEAD-like helicases. It has been proposed that the RWD domain might have a function in protein interaction [[cite:PUB00011448]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: RWD domain-containing protein 1-like [Glycine max] gi|356526049|ref|XP_003531632.1| | 8 | ||
| – | PREDICTED: E3 ubiquitin-protein ligase RNF14-like [Cicer arietinum] gi|502162680|ref|XP_004512580.1| | 23 | ||
| – | E3 ubiquitin-protein ligase RNF14; TAIR: AT1G32340.1 NDR1/HIN1-like 8; Swiss-Prot: sp|Q9JI90|RNF14_MOUSE E3 ubiquitin-protein ligase RNF14; TrEMBL-Plants: tr|V7CJB6|V7CJB6_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0335000 | 25 | ||
| – | E3 ubiquitin-protein ligase RNF14; TAIR: AT1G32340.1 NDR1/HIN1-like 8; Swiss-Prot: sp|Q9JI90|RNF14_MOUSE E3 ubiquitin-protein ligase RNF14; TrEMBL-Plants: tr|G7KDN8|G7KDN8_MEDTR NDR1/HIN1-like protein; Found in the gene: LotjaGi2g1v0335100_LC | 29 | ||
| – | E3 ubiquitin-protein ligase; TAIR: AT3G60300.1 RWD domain-containing protein; Swiss-Prot: sp|Q9QZR0|RNF25_MOUSE E3 ubiquitin-protein ligase RNF25; TrEMBL-Plants: tr|A0A072TK21|A0A072TK21_MEDTR RING finger protein; Found in the gene: LotjaGi3g1v0067500_LC | 16 | ||
| – | RWD domain-containing protein 1; TAIR: AT1G51730.1 Ubiquitin-conjugating enzyme family protein; Swiss-Prot: sp|Q9CQK7|RWDD1_MOUSE RWD domain-containing protein 1; TrEMBL-Plants: tr|K7L7P5|K7L7P5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0428000 | 11 | ||
| – | Protein kinase family protein; TAIR: AT3G59410.4 protein kinase family protein; Swiss-Prot: sp|Q9LX30|GCN2_ARATH eIF-2-alpha kinase GCN2; TrEMBL-Plants: tr|A0A151RUS1|A0A151RUS1_CAJCA Putative serine/threonine-protein kinase GCN2; Found in the gene: LotjaGi3g1v0498400 | 32 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 14.29 |