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IPR024738 is a Transcriptional coactivator Hfi1/Transcriptional adapter 1.
<p>The yeast Spt-Ada-Gcn5-Acetyl (SAGA) transferase complex is a multifunctional coactivator involved in multiple cellular processes [[cite:PUB00056234]], including regulation of transcription by RNA polymerase II [[cite:PUB00056231], [cite:PUB00056232]]. It is formed of five major modular subunits and shows a high degree of structural conservation to human TFTC and STAGA [[cite:PUB00056233]]. This entry represents Hfi1 (known as Transcriptional adapter 1, Tada1 in higher eukaryotes), one of the subunits that constitute the SAGA core. It also functions as a component of the SALSA and SLIK complexes.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | SAGA-type complex | A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Uncharacterized protein TCM_036818 [Theobroma cacao] gi|508781959|gb|EOY29215.1| | 5 | ||
| – | Uncharacterized protein TCM_036818 [Theobroma cacao] gi|508781959|gb|EOY29215.1| | 5 | ||
| – | Uncharacterized protein TCM_036818 [Theobroma cacao] gi|508781959|gb|EOY29215.1| | 5 | ||
| – | Uncharacterized protein TCM_000763 [Theobroma cacao] gi|508699743|gb|EOX91639.1| | 4 | ||
| – | Uncharacterized protein TCM_000763 [Theobroma cacao] gi|508699743|gb|EOX91639.1| | 4 | ||
| – | Uncharacterized protein TCM_007200 [Theobroma cacao] gi|508706537|gb|EOX98433.1| | 5 | ||
| – | Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|A6QR06|TADA1_BOVIN Transcriptional adapter 1; TrEMBL-Plants: tr|I1K940|I1K940_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0393800 | 5 | ||
| – | Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|A6QR06|TADA1_BOVIN Transcriptional adapter 1; TrEMBL-Plants: tr|I1K940|I1K940_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0393800 | 5 | ||
| – | Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|A6QR06|TADA1_BOVIN Transcriptional adapter 1; TrEMBL-Plants: tr|I1K940|I1K940_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0393800 | 5 | ||
| – | Transcriptional adapter 1; TAIR: AT2G14850.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q6NWA8|TADA1_DANRE Transcriptional adapter 1; TrEMBL-Plants: tr|K7KPE5|K7KPE5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0096600 | 4 | ||
| – | Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q12060|HFI1_YEAST Transcriptional coactivator HFI1/ADA1; TrEMBL-Plants: tr|I1M9S8|I1M9S8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0066300 | 5 | ||
| – | Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q12060|HFI1_YEAST Transcriptional coactivator HFI1/ADA1; TrEMBL-Plants: tr|I1M9S8|I1M9S8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0066300 | 5 | ||
| – | Transcriptional adapter 1; TAIR: AT4G33890.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q6DEW4|TADA1_XENTR Transcriptional adapter 1; TrEMBL-Plants: tr|A0A0L9U0A8|A0A0L9U0A8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0323700 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 7.69 |