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IPR026028

Description

IPR026028 is a ATPase, V0 complex, subunit 116kDa, eukaryotic.

<p>Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some transmembrane ATPases also work in reverse, harnessing the energy from a proton gradient, using the flux of ions across the membrane via the ATPase proton channel to drive the synthesis of ATP.</p> <p>This entry represent eukaryotic V-ATPase 116kDa subunit (also known as subunit a). V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex [[cite:PUB00063566]]. V-ATPase 116kDa subunit is part of the integral membrane V0 complex of vacuolar ATPase and is essential for assembly and catalytic activity [[cite:PUB00059278], [cite:PUB00099348]]. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Cellular component Vacuolar proton-transporting V-type ATPase, V0 domain The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.

Associated Lotus transcripts 9

Transcript Name Description Predicted domains Domain count
PREDICTED: V-type proton ATPase 116 kDa subunit a isoform 1-like [Glycine max] gi|356558433|ref|XP_003547511.1| 11
PREDICTED: V-type proton ATPase 116 kDa subunit a isoform 1-like [Glycine max] gi|356542569|ref|XP_003539739.1| 11
V-type proton ATPase subunit a; TAIR: AT4G39080.1 vacuolar proton ATPase A3; Swiss-Prot: sp|Q8W4S4|VHAA3_ARATH V-type proton ATPase subunit a3; TrEMBL-Plants: tr|A0A151RQM9|A0A151RQM9_CAJCA V-type proton ATPase subunit a; Found in the gene: LotjaGi1g1v0424500 11
V-type proton ATPase subunit a; TAIR: AT2G28520.1 vacuolar proton ATPase A1; Swiss-Prot: sp|Q8RWZ7|VHAA1_ARATH V-type proton ATPase subunit a1; TrEMBL-Plants: tr|I1LR08|I1LR08_SOYBN V-type proton ATPase subunit a; Found in the gene: LotjaGi2g1v0364600 11
V-type proton ATPase subunit a; TAIR: AT2G28520.1 vacuolar proton ATPase A1; Swiss-Prot: sp|Q8RWZ7|VHAA1_ARATH V-type proton ATPase subunit a1; TrEMBL-Plants: tr|K7M9K9|K7M9K9_SOYBN V-type proton ATPase subunit a; Found in the gene: LotjaGi3g1v0273900 11
V-type proton ATPase subunit a; TAIR: AT2G28520.1 vacuolar proton ATPase A1; Swiss-Prot: sp|Q8RWZ7|VHAA1_ARATH V-type proton ATPase subunit a1; TrEMBL-Plants: tr|A0A0S3SGJ3|A0A0S3SGJ3_PHAAN V-type proton ATPase subunit a; Found in the gene: LotjaGi3g1v0273900 11
V-type proton ATPase subunit a; TAIR: AT2G28520.1 vacuolar proton ATPase A1; Swiss-Prot: sp|Q8RWZ7|VHAA1_ARATH V-type proton ATPase subunit a1; TrEMBL-Plants: tr|A0A0S3SGJ3|A0A0S3SGJ3_PHAAN V-type proton ATPase subunit a; Found in the gene: LotjaGi3g1v0273900 11
V-type proton ATPase subunit a; TAIR: AT4G39080.1 vacuolar proton ATPase A3; Swiss-Prot: sp|Q8W4S4|VHAA3_ARATH V-type proton ATPase subunit a3; TrEMBL-Plants: tr|B0BL94|B0BL94_LOTJA V-type proton ATPase subunit a; Found in the gene: LotjaGi3g1v0512800 11
V-type proton ATPase subunit a; TAIR: AT4G39080.1 vacuolar proton ATPase A3; Swiss-Prot: sp|Q8W4S4|VHAA3_ARATH V-type proton ATPase subunit a3; TrEMBL-Plants: tr|B0BL94|B0BL94_LOTJA V-type proton ATPase subunit a; Found in the gene: LotjaGi3g1v0512800 11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TRANSMEMBRANE Phobius 1 11.11