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IPR027353 is a NET domain.
<p>The bromodomain and extraterminal (BET) proteins are a class of transcriptional regulators whose members can be found in animals, plants and fungi. BET proteins are involved in diverse cellular phenomena such as meiosis, cell-cycle control, and homeosis and have been suggested to modulate chromatin structure and affect transcription via a sequence-independent mechanism. BET proteins are defined as having one (plants) or two (animals/yeast) bromodomains and an Extra Terminal (ET) domain. The ET domain consists of three separate regions, only one of which, the N-terminal ET (NET) domain is conserved in all BET proteins. The function of the NET domain is assumed to be protein binding [[cite:PUB00063925], [cite:PUB00063926], [cite:PUB00063927], [cite:PUB00063928]].</p> <p>The structure of the NET domain comprises three α-helices and a characteristic loop region of an irregular but well-defined structure. The NET structure has an acidic patch that forms a continuous ridge with a hydrophobic cleft. which may interact with other proteins and/or DNA [[cite:PUB00063928]].</p> <p>Some proteins known to contain a NET domain include:</p> <ul> <li>Human RING3 (now designated Brd2)</li> <li>Murine MCAP (now designated Brd4)</li> <li>Drosophila Fsh</li> <li>Yeast Bdf1 and Bdf2</li> <li>Arabidopsis imbibition-inducible (IMB1), whichplays a role in abscisic acid (ABA) and phytochrome A (phyA) mediated responses of seed germination.</li> </ul>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: transcription factor GTE1-like [Cicer arietinum] gi|502086469|ref|XP_004488228.1| | 13 | ||
| – | PREDICTED: transcription factor GTE1-like isoform X1 [Cicer arietinum] gi|502154173|ref|XP_004509610.1| | 14 | ||
| – | Global transcription factor group [Populus trichocarpa] gi|224098028|ref|XP_002311109.1| | 5 | ||
| – | PREDICTED: transcription factor GTE4-like isoform X1 [Cicer arietinum] gi|502143906|ref|XP_004505511.1| | 15 | ||
| – | PREDICTED: transcription factor GTE10-like [Glycine max] gi|356508786|ref|XP_003523135.1| | 18 | ||
| – | PREDICTED: transcription factor GTE10-like [Glycine max] gi|356508786|ref|XP_003523135.1| | 15 | ||
| – | Transcription factor GTE6 [Medicago truncatula] gi|357504047|ref|XP_003622312.1| | 4 | ||
| – | Transcription factor GTE6 [Medicago truncatula] gi|357504047|ref|XP_003622312.1| | 4 | ||
| – | PREDICTED: transcription factor GTE8-like [Glycine max] gi|356560519|ref|XP_003548539.1| | 15 | ||
| – | PREDICTED: transcription factor GTE8-like [Glycine max] gi|356560519|ref|XP_003548539.1| | 15 | ||
| – | PREDICTED: transcription factor GTE4-like [Glycine max] gi|356546972|ref|XP_003541893.1| | 14 | ||
| – | PREDICTED: transcription factor GTE4-like [Glycine max] gi|356546972|ref|XP_003541893.1| | 6 | ||
| – | PREDICTED: transcription factor GTE7-like isoform X1 [Cicer arietinum] gi|502142265|ref|XP_004504873.1| | 15 | ||
| – | PREDICTED: transcription factor GTE7-like isoform X1 [Cicer arietinum] gi|502142265|ref|XP_004504873.1| | 15 | ||
| – | PREDICTED: transcription factor GTE8-like [Glycine max] gi|356513665|ref|XP_003525531.1| | 15 | ||
| – | PREDICTED: transcription factor GTE11-like [Glycine max] gi|356554838|ref|XP_003545749.1| | 15 | ||
| – | Transcription factor GTE10; TAIR: AT5G63320.1 nuclear protein X1; Swiss-Prot: sp|Q9FGW9|GTE10_ARATH Transcription factor GTE10; TrEMBL-Plants: tr|V7AWA8|V7AWA8_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0235400 | 19 | ||
| – | Transcription factor GTE1; TAIR: AT5G40600.4 bromodomain testis-specific protein; Swiss-Prot: sp|Q9FT54|GTE6_ARATH Transcription factor GTE6; TrEMBL-Plants: tr|A0A0B2NX09|A0A0B2NX09_GLYSO Transcription factor GTE1; Found in the gene: LotjaGi1g1v0614700 | 8 | ||
| – | Transcription factor GTE1; TAIR: AT5G40600.4 bromodomain testis-specific protein; Swiss-Prot: sp|Q9FT54|GTE6_ARATH Transcription factor GTE6; TrEMBL-Plants: tr|A0A0B2NX09|A0A0B2NX09_GLYSO Transcription factor GTE1; Found in the gene: LotjaGi1g1v0614700 | 8 | ||
| – | Transcription factor GTE8; TAIR: AT3G27260.4 global transcription factor group E8; Swiss-Prot: sp|Q9LK27|GTE8_ARATH Transcription factor GTE8; TrEMBL-Plants: tr|A0A0S3RVN8|A0A0S3RVN8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0619600 | 19 | ||
| – | Transcription factor GTE8; TAIR: AT3G27260.4 global transcription factor group E8; Swiss-Prot: sp|Q9LK27|GTE8_ARATH Transcription factor GTE8; TrEMBL-Plants: tr|I1MLM9|I1MLM9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0619700 | 19 | ||
| – | Transcription factor GTE1; TAIR: AT2G34900.1 Transcription factor GTE6; Swiss-Prot: sp|Q84XV2|GTE1_ARATH Transcription factor GTE1; TrEMBL-Plants: tr|V7C0T4|V7C0T4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0101800 | 17 | ||
| – | Transcription factor GTE4; TAIR: AT1G06230.1 global transcription factor group E4; Swiss-Prot: sp|Q9LNC4|GTE4_ARATH Transcription factor GTE4; TrEMBL-Plants: tr|K7KXX1|K7KXX1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0246800 | 19 | ||
| – | Transcription factor GTE4; TAIR: AT1G06230.1 global transcription factor group E4; Swiss-Prot: sp|Q9LNC4|GTE4_ARATH Transcription factor GTE4; TrEMBL-Plants: tr|K7M2K1|K7M2K1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0449500 | 18 | ||
| – | Transcription factor GTE4; TAIR: AT1G73150.1 global transcription factor group E3; Swiss-Prot: sp|Q9S7T1|GTE3_ARATH Transcription factor GTE3, chloroplastic; TrEMBL-Plants: tr|A0A0L9VGU3|A0A0L9VGU3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0042000 | 19 | ||
| – | Transcription factor GTE4; TAIR: AT1G73150.1 global transcription factor group E3; Swiss-Prot: sp|Q9S7T1|GTE3_ARATH Transcription factor GTE3, chloroplastic; TrEMBL-Plants: tr|A0A0L9VGU3|A0A0L9VGU3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0042000 | 19 | ||
| – | Transcription factor GTE1; TAIR: AT2G34900.1 Transcription factor GTE6; Swiss-Prot: sp|Q84XV2|GTE1_ARATH Transcription factor GTE1; TrEMBL-Plants: tr|A0A0S3R458|A0A0S3R458_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0150600 | 18 | ||
| – | Transcription factor GTE10; TAIR: AT5G63320.1 nuclear protein X1; Swiss-Prot: sp|Q9FGW9|GTE10_ARATH Transcription factor GTE10; TrEMBL-Plants: tr|K7KMV6|K7KMV6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0223700 | 19 | ||
| – | Transcription factor GTE10; TAIR: AT5G63320.1 nuclear protein X1; Swiss-Prot: sp|Q9FGW9|GTE10_ARATH Transcription factor GTE10; TrEMBL-Plants: tr|K7KMV6|K7KMV6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0223700 | 19 | ||
| – | Transcription factor GTE1; TAIR: AT2G34900.1 Transcription factor GTE6; Swiss-Prot: sp|Q84XV2|GTE1_ARATH Transcription factor GTE1; TrEMBL-Plants: tr|A0A0S3RIF5|A0A0S3RIF5_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0247400 | 18 | ||
| – | Transcription factor GTE4; TAIR: AT1G73150.1 global transcription factor group E3; Swiss-Prot: sp|Q9S7T1|GTE3_ARATH Transcription factor GTE3, chloroplastic; TrEMBL-Plants: tr|A0A0L9VGU3|A0A0L9VGU3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0347400 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 3.23 |