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IPR033753

Source: InterPro

Description

IPR033753 is a Glycine cleavage system H-protein/Simiate.

<p>This is a family of glycine cleavage H-proteins, part of the glycine cleavage system (GCS) found in bacteria, archaea, and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and L-proteins) which catalyzes the oxidative cleavage of glycine [[cite:PUB00063633]]. The H-protein shuttles the methylamine group of glycine from the P-protein (glycine dehydrogenase) to the T-protein (aminomethyltransferase) via a lipoyl group, attached to a completely conserved lysine residue [[cite:PUB00004842]].</p> <p>This enty includes Abitram proteins. Abitram (also known as Simiate) functions in transcription regulation [[cite:PUB00080907]]. Furthermore, it associates with both G- and F-Actin and affects actin polymerization and actin turnover, influencing filopodia dynamics and arborization of neurons [[cite:PUB00080908]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 6

Transcript Name Description Predicted domains Domain count
Lj1g3v2239520.1
– PREDICTED: protein FAM206A-like isoform 1 [Glycine max] gi|356517742|ref|XP_003527545.1|
Domains
7
Lj4g3v0654460.1
– PREDICTED: glycine cleavage system H protein, mitochondrial-like [Cicer arietinum] gi|502143341|ref|XP_004505304.1|
Domains
16
Lj4g3v1152920.1
– PREDICTED: ent-kaurenoic acid oxidase 2-like [Glycine max] gi|356495547|ref|XP_003516638.1|
Domains
19
LotjaGi1g1v0431300.1
– Glycine cleavage system H protein; TAIR: AT1G75980.1 Single hybrid motif superfamily protein; Swiss-Prot: sp|Q80ZQ9|F206A_MOUSE Protein Simiate; TrEMBL-Plants: tr|V7AR19|V7AR19_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0431300
Domains
7
LotjaGi2g1v0415700.1
– Glycine cleavage system h protein; TAIR: AT1G32470.1 Single hybrid motif superfamily protein; Swiss-Prot: sp|Q39732|GCSH_FLAAN Glycine cleavage system H protein, mitochondrial; TrEMBL-Plants: tr|I3SRF4|I3SRF4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0415700
Domains
16
LotjaGi4g1v0083600.2
– Glycine cleavage system H family protein; TAIR: AT2G35120.1 Single hybrid motif superfamily protein; Swiss-Prot: sp|O82179|GCSH2_ARATH Glycine cleavage system H protein 2, mitochondrial; TrEMBL-Plants: tr|I3S7G1|I3S7G1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0083600
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd06848 CDD 1 16.67