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IPR034131

Source: InterPro

Description

IPR034131 is a DAZ-associated protein 1, RNA recognition motif 2.

<p>This entry represents the RNA recognition motif 2 of DAZAP1.</p> <p>DAZAP1, initially identified as a binding partner of Deleted in Azoospermia (DAZ), is a multi-functional ubiquitous RNA-binding protein expressed most abundantly in the testis and is essential for normal cell growth, development, and spermatogenesis [[cite:PUB00082731], [cite:PUB00082729]]. DAZAP1 is a shuttling protein whose acetylated form is predominantly nuclear and the nonacetylated form is in cytoplasm [[cite:PUB00082732]]. DAZAP1 also functions as a translational regulator that activates translation in an mRNA-specific manner [[cite:PUB00082733]]. It also interacts with numerous hnRNPs, including hnRNP U, hnRNP U like-1, hnRNPA1, hnRNPA/B, and hnRNP D, suggesting DAZAP1 might associate and cooperate with hnRNP particles to regulate adenylate-uridylate-rich elements (AU-rich element or ARE)-containing mRNAs [[cite:PUB00082732], [cite:PUB00082730]]. DAZAP1 contains two N-terminal RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), and a C-terminal proline-rich domain [[cite:PUB00082731]].</p> <p>This entry also includes the orthologue from Drosophila melanogaster Heterogeneous nuclear ribonucleoprotein 27C (Rbp7).</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003723
Molecular function RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
Subterm of

Associated Lotus transcripts 10

Transcript Name Description Predicted domains Domain count
LotjaGi1g1v0007900.1
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|A0A0B2SI74|A0A0B2SI74_GLYSO DAZ-associated protein 1; Found in the gene: LotjaGi1g1v0007900
Domains
14
LotjaGi1g1v0007900.2
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|A0A0B2SI74|A0A0B2SI74_GLYSO DAZ-associated protein 1; Found in the gene: LotjaGi1g1v0007900
Domains
14
LotjaGi1g1v0021200.1
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|A0A0B2QW64|A0A0B2QW64_GLYSO RNA-binding protein Musashi like Rbp6; Found in the gene: LotjaGi1g1v0021200
Domains
14
LotjaGi1g1v0021200.2
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|A0A0B2QW64|A0A0B2QW64_GLYSO RNA-binding protein Musashi like Rbp6; Found in the gene: LotjaGi1g1v0021200
Domains
14
LotjaGi1g1v0021200.3
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|A0A0B2QW64|A0A0B2QW64_GLYSO RNA-binding protein Musashi like Rbp6; Found in the gene: LotjaGi1g1v0021200
Domains
14
LotjaGi5g1v0158700.1
– RNA-binding protein-like; TAIR: AT2G33410.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|I1NI06|I1NI06_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0158700
Domains
14
LotjaGi6g1v0149600_LC.1
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|V7BNH4|V7BNH4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0149600_LC
Domains
14
LotjaGi6g1v0149600_LC.3
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|V7BNH4|V7BNH4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0149600_LC
Domains
14
LotjaGi6g1v0149600_LC.5
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|V7BNH4|V7BNH4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0149600_LC
Domains
14
LotjaGi6g1v0285100.1
– RNA-binding protein, putative; TAIR: AT3G07810.1 RNA-binding (RRM/RBD/RNP motifs) family protein; Swiss-Prot: sp|Q8W034|RNP1_ARATH Heterogeneous nuclear ribonucleoprotein 1; TrEMBL-Plants: tr|G7IP95|G7IP95_MEDTR RNA-binding (RRM/RBD/RNP motif) family protein; Found in the gene: LotjaGi6g1v0285100
Domains
14

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 10.00