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IPR034922 is a RNA exonuclease 1-like, exonuclease domain.
<p>Proteins containing this domain are composed of RNA exonuclease 1 (REX1 or Rex1p), REX3 (or Rex3p), and similar eukaryotic proteins. In yeast, REX1 and REX3 are required for 5S rRNA and MRP (mitochondrial RNA processing) RNA maturation, respectively [[cite:PUB00084623]]. They are DEDDh-type DnaQ-like 3'-5' exonucleases containing three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis [[cite:PUB00084622]].</p> <p>REX1 is the major exonuclease from this family responsible for pre-tRNA trail trimming and may also be involved in nuclear CCA turnover [[cite:PUB00084628]]. REX proteins function in the processing and maturation of many RNA species, similar to the function of Escherichia coli RNase T [[cite:PUB00084622]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Small RNA degrading nuclease; TAIR: AT5G25800.1 Polynucleotidyl transferase, ribonuclease H-like superfamily protein; Swiss-Prot: sp|Q8L7M4|SDN5_ARATH Small RNA degrading nuclease 5; TrEMBL-Plants: tr|I1LXA9|I1LXA9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0167200 | 12 | ||
| – | Small RNA degrading nuclease; TAIR: AT5G25800.1 Polynucleotidyl transferase, ribonuclease H-like superfamily protein; Swiss-Prot: sp|Q8L7M4|SDN5_ARATH Small RNA degrading nuclease 5; TrEMBL-Plants: tr|I1LXA9|I1LXA9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0167200 | 11 | ||
| – | Small RNA degrading nuclease; TAIR: AT5G25800.1 Polynucleotidyl transferase, ribonuclease H-like superfamily protein; Swiss-Prot: sp|Q8L7M4|SDN5_ARATH Small RNA degrading nuclease 5; TrEMBL-Plants: tr|I1LXA9|I1LXA9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0167200 | 11 | ||
| – | Small RNA degrading nuclease; TAIR: AT5G67240.3 small RNA degrading nuclease 3; Swiss-Prot: sp|Q8RXK2|SDN3_ARATH Small RNA degrading nuclease 3; TrEMBL-Plants: tr|I3SLN1|I3SLN1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0680300 | 12 | ||
| – | Small RNA degrading nuclease; TAIR: AT5G67240.1 small RNA degrading nuclease 3; Swiss-Prot: sp|Q8RXK2|SDN3_ARATH Small RNA degrading nuclease 3; TrEMBL-Plants: tr|I3SLN1|I3SLN1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0008300 | 12 | ||
| – | Small RNA degrading nuclease; TAIR: AT5G67240.1 small RNA degrading nuclease 3; Swiss-Prot: sp|Q8RXK2|SDN3_ARATH Small RNA degrading nuclease 3; TrEMBL-Plants: tr|I3SLN1|I3SLN1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0008300 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd06145 | CDD | 1 | 16.67 |