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IPR036909 is a Cytochrome c-like domain superfamily.
<p>After cytochrome c is synthesized in the cytoplasm as apocytochrome c, it is transported through the outer mitochondrial membrane to the intermembrane space, where haem is covalently attached by thioester bonds to two cysteine residues located in the cytochrome c centre. Cytochrome c is required during oxidative phosphorylation as an electron shuttle between Complex III (cytochrome c reductase) and IV (cytochrome c oxidase). In addition, cytochrome c is involved in apoptosis in more complex organisms such as Xenopus, rats and humans. Cellular stress can induce cytochrome c release from the mitochondrial membrane. In mammals, cytochrome c triggers the assembly of the apoptosome, consisting of cytochrome c, Apaf-1 and dATP, which activates caspase-9, leading to cell death [[cite:PUB00013190], [cite:PUB00016256]]. There are several different members of the cytochrome c family with different functional roles, for instance cytochrome c549 is associated with photosystem II [[cite:PUB00013307]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Electron transfer activity | Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient. | ||
| Molecular function | Heme binding | Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Cytochrome c; TAIR: AT4G10040.1 cytochrome c-2; Swiss-Prot: sp|P00051|CYC_CUCMA Cytochrome c; TrEMBL-Plants: tr|I3T359|I3T359_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0489900 | 10 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|A0A0B2PL84|A0A0B2PL84_GLYSO Cytochrome c1-1, heme protein, mitochondrial; Found in the gene: LotjaGi2g1v0084500 | 21 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|A0A1J7GJ50|A0A1J7GJ50_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0084500 | 21 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|A0A1J7GJ50|A0A1J7GJ50_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0084500 | 21 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|A0A1J7GJ50|A0A1J7GJ50_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0084500 | 21 | ||
| – | Cytochrome c; TAIR: AT4G10040.1 cytochrome c-2; Swiss-Prot: sp|P00052|CYC_VIGRR Cytochrome c; TrEMBL-Plants: tr|I3SL85|I3SL85_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0446000 | 10 | ||
| – | Cytochrome c6; TAIR: AT5G45040.1 Cytochrome c; Swiss-Prot: sp|Q93VA3|CYC6_ARATH Cytochrome c6, chloroplastic; TrEMBL-Plants: tr|I3SY34|I3SY34_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0084500 | 8 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|I3S7F6|I3S7F6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0132800 | 17 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|I3S7F6|I3S7F6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0132800 | 21 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|I3S7F6|I3S7F6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0132800 | 17 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|I3S7F6|I3S7F6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0132800 | 21 | ||
| – | Cytochrome c1, heme protein, mitochondrial; TAIR: AT5G40810.1 Cytochrome C1 family; Swiss-Prot: sp|P25076|CY11_SOLTU Cytochrome c1-1, heme protein, mitochondrial; TrEMBL-Plants: tr|I3S7F6|I3S7F6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0132800 | 21 | ||
| – | Cytochrome c; TAIR: AT4G10040.1 cytochrome c-2; Swiss-Prot: sp|P00051|CYC_CUCMA Cytochrome c; TrEMBL-Plants: tr|I3T359|I3T359_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0216000 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF46626 | SUPERFAMILY | 1 | 7.69 |