Domain Predictions — View

Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR041094

Source: InterPro

Description

IPR041094 is a Brr2, N-terminal helicase PWI domain.

<p>This domain is found in spliceosomal RNA helicase Brr2 and its homologues. Brr2 is required for the assembly of a catalytically active spliceosome on a messenger RNA precursor. It plays an essential role in pre-mRNA splicing as a core component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes [[cite:PUB00090272], [cite:PUB00101924], [cite:PUB00101923], [cite:PUB00101922]]. Brr2 catalyses the ATP-dependent unwinding of U4/U6 RNA duplexes, an essential step in the assembly of a catalytically active spliceosome [[cite:PUB00101900]]. The domain is found in the N-terminal region and is non-canonically PWI-like. The PWI-like domain is thought to be involved in protein-protein interactions [[cite:PUB00091439]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 3

Transcript	Name	Description	Predicted domains	Domain count
LotjaGi3g1v0141500.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	U5 small nuclear ribonucleoprotein helicase; TAIR: AT1G20960.1 U5 small nuclear ribonucleoprotein helicase; Swiss-Prot: sp\|Q9SYP1\|DEXHC_ARATH DExH-box ATP-dependent RNA helicase DExH12; TrEMBL-Plants: tr\|A0A0L9UIS3\|A0A0L9UIS3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0141500	Domains Coil G3DSA:1.10.10.2530 G3DSA:1.10.150.20 G3DSA:1.10.3380.10 G3DSA:2.60.40.150 G3DSA:3.40.50.300 IPR001650 IPR003593 IPR004179 IPR011545 IPR014001 IPR014756 IPR027417 IPR035892 IPR036390 IPR041094 PF00270 PF00271 PF02889 PF18149 PIRSF039073 PS51192 PS51194 PTHR12131 PTHR12131:SF12 SM00382 SM00487 SM00490 SM00973 SSF158702 SSF46785 SSF52540 SSF81296 cd18019 cd18021 cd18795 mobidb-lite	37
LotjaGi3g1v0141500.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	U5 small nuclear ribonucleoprotein helicase; TAIR: AT1G20960.1 U5 small nuclear ribonucleoprotein helicase; Swiss-Prot: sp\|Q9SYP1\|DEXHC_ARATH DExH-box ATP-dependent RNA helicase DExH12; TrEMBL-Plants: tr\|A0A0L9UIS3\|A0A0L9UIS3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0141500	Domains Coil G3DSA:1.10.10.2530 G3DSA:1.10.150.20 G3DSA:1.10.3380.10 G3DSA:2.60.40.150 G3DSA:3.40.50.300 IPR001650 IPR003593 IPR004179 IPR011545 IPR014001 IPR014756 IPR027417 IPR035892 IPR036390 IPR041094 PF00270 PF00271 PF02889 PF18149 PIRSF039073 PS51192 PS51194 PTHR12131 PTHR12131:SF12 SM00382 SM00487 SM00490 SM00973 SSF158702 SSF46785 SSF52540 SSF81296 cd18019 cd18021 cd18795 mobidb-lite	37
LotjaGi5g1v0347000_LC.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	U5 small nuclear ribonucleoprotein helicase; TAIR: AT1G20960.1 U5 small nuclear ribonucleoprotein helicase; Swiss-Prot: sp\|Q9SYP1\|DEXHC_ARATH DExH-box ATP-dependent RNA helicase DExH12; TrEMBL-Plants: tr\|A0A067DX77\|A0A067DX77_CITSI Uncharacterized protein; Found in the gene: LotjaGi5g1v0347000_LC	Domains IPR041094 PF18149 PTHR12131 PTHR12131:SF12	4

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
PTHR12131:SF12	PANTHER	1	33.33