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Mini-chromosome maintenance (MCM) protein 2 signature
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). | ||
| Molecular function | ATP binding | Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | ||
| Cellular component | Nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. | ||
| Biological process | DNA replication initiation | The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate. | ||
| Cellular component | MCM complex | A hexameric protein complex required for the initiation and regulation of DNA replication. | ||
| Biological process | Negative regulation of DNA helicase activity | Any process that stops, prevents or reduces the frequency, rate or extent of DNA helicase activity. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: DNA replication licensing factor mcm2-like [Glycine max] gi|356521757|ref|XP_003529518.1| | 25 | ||
| – | DNA helicase; TAIR: AT1G44900.1 minichromosome maintenance (MCM2/3/5) family protein; Swiss-Prot: sp|B8BKI8|MCM2_ORYSI DNA replication licensing factor MCM2; TrEMBL-Plants: tr|V7C891|V7C891_PHAVU DNA helicase; Found in the gene: LotjaGi4g1v0332400 | 29 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |