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mito_nad_idh: isocitrate dehydrogenase, NAD-dependent
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Isocitrate dehydrogenase (NAD+) activity | Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+. | ||
| Biological process | Tricarboxylic acid cycle | A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: isocitrate dehydrogenase [NAD] gi|356559222|ref|XP_003547899.1| | 10 | ||
| – | Isocitrate dehydrogenase, putative; TAIR: AT4G35260.1 isocitrate dehydrogenase 1; Swiss-Prot: sp|Q8LFC0|IDH1_ARATH Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; TrEMBL-Plants: tr|I1LI93|I1LI93_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0356600 | 9 | ||
| – | 3-isopropylmalate dehydrogenase; TAIR: AT4G35260.1 isocitrate dehydrogenase 1; Swiss-Prot: sp|Q8LFC0|IDH1_ARATH Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; TrEMBL-Plants: tr|A0A0R0HDU0|A0A0R0HDU0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0356600 | 9 | ||
| – | 3-isopropylmalate dehydrogenase; TAIR: AT4G35260.1 isocitrate dehydrogenase 1; Swiss-Prot: sp|Q8LFC0|IDH1_ARATH Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; TrEMBL-Plants: tr|G7L9H2|G7L9H2_MEDTR NAD-dependent isocitrate dehydrogenase; Found in the gene: LotjaGi4g1v0137200 | 9 | ||
| – | 3-isopropylmalate dehydrogenase; TAIR: AT4G35260.1 isocitrate dehydrogenase 1; Swiss-Prot: sp|Q8LFC0|IDH1_ARATH Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; TrEMBL-Plants: tr|I1MMY0|I1MMY0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0137200 | 9 | ||
| – | Isopropylmalate dehydrogenase; TAIR: AT5G03290.1 isocitrate dehydrogenase V; Swiss-Prot: sp|Q945K7|IDH5_ARATH Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; TrEMBL-Plants: tr|I3SWL7|I3SWL7_LOTJA Isocitrate dehydrogenase [NAD] subunit, mitochondrial; Found in the gene: LotjaGi5g1v0080100 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00175 | TIGRFAM | 1 | 16.67 |