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GO:0031931

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description TORC1 complex
Full defintion A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.
Subterm of

Relationships

The relationship of GO:0031931 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCjh
PMID
Amino acid signaling in TOR activation.Kim J, Guan KL
Annu Rev Biochem. 2011; 80 (): 1001–32.PMID: 21548787

The target of rapamycin (TOR) is a central cell growth regulator conserved from yeast to mammals. Uncontrolled TOR activation is commonly observed in human cancers. TOR forms two distinct structural and functional complexes, TORC1 and TORC2. TORC1 promotes cell growth and cell size by stimulating protein synthesis. A wide range of signals, including nutrients, energy levels, and growth factors, are known to control TORC1 activity. Among them, amino acids (AA) not only potently activate TORC1 but are also required for TORC1 activation by other stimuli, such as growth factors. The mechanisms of growth factors and cellular energy status in activating TORC1 have been well elucidated, whereas the molecular basis of AA signaling is just emerging. Recent advances in the role of AA signaling on TORC1 activation have revealed key components, including the Rag GTPases, protein kinases, nutrient transporters, and the intracellular trafficking machinery, in relaying AA signals to TORC1 activation.

Associated Lotus transcripts 16

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj1g3v2442920.1
– PREDICTED: regulatory-associated protein of TOR 1-like [Glycine max] gi|356530199|ref|XP_003533671.1|
GO terms
2
Lj1g3v2442920.2
– PREDICTED: regulatory-associated protein of TOR 1-like [Glycine max] gi|356530199|ref|XP_003533671.1|
GO terms
2
Lj1g3v2442920.3
– PREDICTED: regulatory-associated protein of TOR 1-like isoform X2 [Cicer arietinum] gi|502104405|ref|XP_004492529.1|
GO terms
2
Lj1g3v2442920.4
– PREDICTED: regulatory-associated protein of TOR 1-like [Glycine max] gi|356530199|ref|XP_003533671.1|
GO terms
2
LotjaGi1g1v0452200.1
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.10
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.2
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.3
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.4
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.5
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.6
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.7
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.8
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi1g1v0452200.9
– Regulatory-associated protein of TOR 1; TAIR: AT3G08850.1 Regulatory-associated protein of TOR 1; Swiss-Prot: sp|Q93YQ1|RTOR1_ARATH Regulatory-associated protein of TOR 1; TrEMBL-Plants: tr|V7B2P2|V7B2P2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0452200
GO terms
2
LotjaGi6g1v0320200.1
– WD40 repeat-like protein; TAIR: AT3G18140.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q54D08|LST8_DICDI Protein LST8 homolog; TrEMBL-Plants: tr|I3S6V4|I3S6V4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0320200
GO terms
3
LotjaGi6g1v0320200.2
– WD40 repeat-like protein; TAIR: AT3G18140.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q54D08|LST8_DICDI Protein LST8 homolog; TrEMBL-Plants: tr|I3S6V4|I3S6V4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0320200
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0031932
Cellular component TORC2 complex 1 6.25