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IPR004328 is a BRO1 domain.
<p>The BRO1 domain is a protein domain of ~390 residues in length. It occurs in a number of eukaryotic proteins, such as yeast BRO1 and human PDCD6IP/Alix, which are involved in protein targeting to the vacuole or lysosome. The BRO1 domain of fungal and mammalian proteins binds with multivesicular body components (ESCRT-III proteins) such as yeast Snf7 and mammalian CHMP4b, and can function to target BRO1 domain-containing proteins to endosomes [[cite:PUB00021037], [cite:PUB00019524], [cite:PUB00033714]].</p> <p>The BRO1 domain has a boomerang shape composed of 14 α-helices and 3 β-sheets. It contains a TPR-like substructure in the central part [[cite:PUB00021037]]. The C terminus is less conserved.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Endosomal targeting BRO1-like domain-containing protein isoform 2 [Theobroma cacao] gi|508774320|gb|EOY21576.1| | 12 | ||
| – | PREDICTED: ALG-2 interacting protein X-like [Glycine max] gi|356536236|ref|XP_003536645.1| | 15 | ||
| – | BRO1 domain-containing protein BROX [Medicago truncatula] gi|357508279|ref|XP_003624428.1| | 8 | ||
| – | Endosomal targeting BRO1-like domain-containing protein isoform 2 [Theobroma cacao] gi|508774320|gb|EOY21576.1| | 11 | ||
| – | PREDICTED: programmed cell death 6-interacting protein-like [Glycine max] gi|356502464|ref|XP_003520039.1| | 8 | ||
| – | PREDICTED: programmed cell death 6-interacting protein-like [Glycine max] gi|356502464|ref|XP_003520039.1| | 8 | ||
| – | Endosomal targeting BRO1-like domain-containing protein isoform 2 [Theobroma cacao] gi|508774320|gb|EOY21576.1| | 9 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT5G14020.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q4V8K5|BROX_RAT BRO1 domain-containing protein BROX; TrEMBL-Plants: tr|A0A151T941|A0A151T941_CAJCA BRO1 domain-containing protein BROX isogeny; Found in the gene: LotjaGi1g1v0630300 | 10 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q7SAN9|BRO1_NEUCR Vacuolar protein-sorting protein bro-1; TrEMBL-Plants: tr|A0A151T3S3|A0A151T3S3_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0174000 | 13 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q7SAN9|BRO1_NEUCR Vacuolar protein-sorting protein bro-1; TrEMBL-Plants: tr|A0A151T3S3|A0A151T3S3_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0174000 | 13 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q7SAN9|BRO1_NEUCR Vacuolar protein-sorting protein bro-1; TrEMBL-Plants: tr|A0A151T3S3|A0A151T3S3_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0174000 | 13 | ||
| – | BRO1 domain-containing protein; TAIR: AT1G13310.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q9W6C5|PDC6I_XENLA Programmed cell death 6-interacting protein; TrEMBL-Plants: tr|A0A151RZB7|A0A151RZB7_CAJCA BRO1 domain-containing protein BROX; Found in the gene: LotjaGi2g1v0280400 | 9 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q4V8K5|BROX_RAT BRO1 domain-containing protein BROX; TrEMBL-Plants: tr|A0A0L9TYL6|A0A0L9TYL6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0198900 | 11 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q4V8K5|BROX_RAT BRO1 domain-containing protein BROX; TrEMBL-Plants: tr|A0A0L9TYL6|A0A0L9TYL6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0198900 | 11 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q4V8K5|BROX_RAT BRO1 domain-containing protein BROX; TrEMBL-Plants: tr|A0A0L9TYL6|A0A0L9TYL6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0198900 | 10 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q4V8K5|BROX_RAT BRO1 domain-containing protein BROX; TrEMBL-Plants: tr|A0A072VNC3|A0A072VNC3_MEDTR Endosomal targeting BRO1-like domain protein; Found in the gene: LotjaGi5g1v0198900 | 10 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q4V8K5|BROX_RAT BRO1 domain-containing protein BROX; TrEMBL-Plants: tr|A0A0L9TYL6|A0A0L9TYL6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0198900 | 11 | ||
| – | Endosomal targeting BRO1-like domain protein; TAIR: AT1G73390.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|P26955|IL3RB_MOUSE Cytokine receptor common subunit beta; TrEMBL-Plants: tr|A0A0L9TYL6|A0A0L9TYL6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0198900 | 11 | ||
| – | ALG-2 interacting protein X; TAIR: AT1G15130.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q8T7K0|ALIX_DICDI ALG-2 interacting protein X; TrEMBL-Plants: tr|I1LEN7|I1LEN7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0332400 | 16 | ||
| – | ALG-2 interacting protein X; TAIR: AT1G15130.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q8T7K0|ALIX_DICDI ALG-2 interacting protein X; TrEMBL-Plants: tr|A0A0S3SM52|A0A0S3SM52_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0332400 | 14 | ||
| – | ALG-2 interacting protein X; TAIR: AT1G15130.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q8T7K0|ALIX_DICDI ALG-2 interacting protein X; TrEMBL-Plants: tr|I1LEN7|I1LEN7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0332400 | 16 | ||
| – | ALG-2 interacting protein X; TAIR: AT1G15130.1 Endosomal targeting BRO1-like domain-containing protein; Swiss-Prot: sp|Q8T7K0|ALIX_DICDI ALG-2 interacting protein X; TrEMBL-Plants: tr|I1LEN7|I1LEN7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0332400 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 4.55 |