Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR011129 is a Cold shock domain.
<p>A conserved domain of about 70 amino acids has been found in prokaryotic and eukaryotic single-strand nucleic-acid binding proteins [[cite:PUB00004326], [cite:PUB00004061], [cite:PUB00003861], [cite:PUB00021106], [cite:PUB00028025]]. This domain, which is known as the 'cold-shock domain' (CSD) is present in the proteins listed below.</p> <ul> <li>Escherichia coli protein CS7.4 (gene cspA) which is induced in response to low temperature (cold-shock protein) and which binds to and stimulates the transcription of the CCAAT-containing promoters of the HN-S protein and of gyrA.</li> <li>Transcription termination factor Rho, a prokaryotic protein which facilitates transcription termination.</li> <li>Mammalian Y box binding protein 1 (YB1). A protein that binds to the CCAAT-containing Y box of mammalian HLA class II genes.</li> <li>Xenopus Y box binding proteins -1 and -2 (Y1 and Y2). Proteins that bind to the CCAAT-containing Y box of Xenopus hsp70 genes.</li> <li>Xenopus B box binding protein (YB3). YB3 binds the B box promoter element of genes transcribed by RNA polymerase III.</li> <li>Enhancer factor I subunit A (EFI-A) (dbpB). A protein that also bind to CCAAT-motif in various gene promoters.</li> <li>DbpA, a human DNA-binding protein of unknown specificity.</li> <li>Bacillus subtilis cold-shock proteins cspB and cspC.</li> <li>Streptomyces clavuligerus protein SC 7.0.</li> <li>E. coli proteins cspB, cspC, cspD, cspE and cspF.</li> <li>Unr, a mammalian gene encoded upstream of the N-ras gene. Unr contains nine repeats that are similar to the CSD domain. The function of Unr is not yet known but it could be a multivalent DNA-binding protein.</li> <li>PPPin, a mammalian brain-specific protein that binds to histone mRNA and which is thought to play a role in the regulation of brain development.</li> </ul>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Nucleic acid binding | Interacting selectively and non-covalently with any nucleic acid. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: glycine-rich protein 2-like [Cicer arietinum] gi|502144859|ref|XP_004505774.1| | 16 | ||
| – | PREDICTED: cold shock protein 1-like [Cicer arietinum] gi|502153508|ref|XP_004509364.1| | 20 | ||
| – | PREDICTED: DNA-binding protein HEXBP-like [Glycine max] gi|356559280|ref|XP_003547928.1| | 19 | ||
| – | Cold shock protein; TAIR: AT2G21060.1 glycine-rich protein 2B; Swiss-Prot: sp|Q38896|CSP4_ARATH Cold shock domain-containing protein 4; TrEMBL-Plants: tr|A0A088FZS5|A0A088FZS5_CICAR Cold shock protein; Found in the gene: LotjaGi3g1v0522700 | 20 | ||
| – | Cold shock protein, putative; TAIR: AT4G36020.1 cold shock domain protein 1; Swiss-Prot: sp|O65639|CSP1_ARATH Cold shock protein 1; TrEMBL-Plants: tr|A0A0S3R460|A0A0S3R460_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0128600 | 22 | ||
| – | Cold shock protein; TAIR: AT2G21060.1 glycine-rich protein 2B; Swiss-Prot: sp|P27484|GRP2_NICSY Glycine-rich protein 2; TrEMBL-Plants: tr|F6I111|F6I111_VITVI Putative uncharacterized protein; Found in the gene: LotjaGi5g1v0160000 | 21 | ||
| – | Cold shock protein; TAIR: AT4G36020.2 cold shock domain protein 1; Swiss-Prot: sp|O65639|CSP1_ARATH Cold shock protein 1; TrEMBL-Plants: tr|V7AVE5|V7AVE5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0236800 | 20 | ||
| – | Cold shock protein; TAIR: AT4G36020.1 cold shock domain protein 1; Swiss-Prot: sp|P27484|GRP2_NICSY Glycine-rich protein 2; TrEMBL-Plants: tr|I1LPN7|I1LPN7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0237000_LC | 20 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd04458 | CDD | 1 | 12.50 |