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IPR015679

Source: InterPro

Description

IPR015679 is a Phospholipase D family.

<p>Phospholipase D (PLD) catalyses the hydrolysis of the phosphodiester bond of glycerophospholipids to generate phosphatidic acid and a free head group. Phospholipase D activities have been detected in simple to complex organisms from viruses and bacteria to yeast, plants, and mammals [[cite:PUB00034910]]. In higher organisms, PLD specifically catalyzes the hydrolysis of phosphatidylcholine (PC) to phosphatidic acid (PA) and choline and is activated in response to stimulators of vesicle transport, endocytosis, exocytosis, cell migration, and mitosis.</p> <p>There are two mammalian phospholipase D genes whose products (PLD1 and PLD2) are alternatively spliced. Both forms have two highly conserved HKD motifs that are essential for catalysis and dimerisation [[cite:PUB00034911]]. It has now been observed that there are abnormalities in PLD expression and activity in many human cancers [[cite:PUB00034912]].</p> <p>Most bacteria use an enzyme belonging to the phospholipase D family as cardiolipin synthase. In contrast, eukaryotes and most actinobacteria use a cardiolipin synthase of the CDP-alcohol phosphatidyltransferase family [[cite:PUB00053993]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 53

Transcript Name Description Predicted domains Domain count
Lj0g3v0004479.1
– PREDICTED: phospholipase D beta 1-like [Cicer arietinum] gi|502157483|ref|XP_004510892.1|
Domains
19
Lj0g3v0057229.1
– PREDICTED: phospholipase D beta 1-like [Cicer arietinum] gi|502157483|ref|XP_004510892.1|
Domains
19
Lj0g3v0060819.1
– PREDICTED: phospholipase D epsilon-like [Glycine max] gi|356556716|ref|XP_003546669.1|
Domains
18
Lj0g3v0101819.1
– PREDICTED: phospholipase D delta-like [Glycine max] gi|356495342|ref|XP_003516537.1|
Domains
22
Lj0g3v0244599.1
– Phospholipase D [Pyrus pyrifolia] gi|165911117|gb|ABY74313.1|
Domains
5
Lj0g3v0244639.1
– PREDICTED: phospholipase D alpha 1-like [Cicer arietinum] gi|502147919|ref|XP_004506968.1|
Domains
5
Lj0g3v0244679.1
– Phospholipase D alpha [Medicago truncatula] gi|357468269|ref|XP_003604419.1|
Domains
9
Lj0g3v0335969.1
– PREDICTED: phospholipase D beta 1-like [Glycine max] gi|356502436|ref|XP_003520025.1|
Domains
13
Lj0g3v0363499.1
– PREDICTED: phospholipase D beta 1-like isoform X2 [Cicer arietinum] gi|502104890|ref|XP_004492672.1|
Domains
11
Lj1g3v1911660.1
– Phospholipase D alpha [Medicago truncatula] gi|357466237|ref|XP_003603403.1|
Domains
20
Lj1g3v1911690.1
– Phospholipase D alpha [Medicago truncatula] gi|357466245|ref|XP_003603407.1|
Domains
19
Lj1g3v2264770.1
– Phospholipase D delta [Medicago truncatula] gi|357467115|ref|XP_003603842.1|
Domains
11
Lj1g3v2264780.1
– PREDICTED: phospholipase D delta-like [Glycine max] gi|356509028|ref|XP_003523254.1|
Domains
8
Lj1g3v2264810.1
– PREDICTED: phospholipase D delta-like isoform X2 [Cicer arietinum] gi|502131186|ref|XP_004500904.1|
Domains
3
Lj2g3v1647880.1
– PREDICTED: phospholipase D delta-like [Glycine max] gi|356495342|ref|XP_003516537.1|
Domains
22
Lj2g3v2003100.1
– PREDICTED: phospholipase D gamma 1-like isoform 1 [Glycine max] gi|356497199|ref|XP_003517450.1|
Domains
20
Lj3g3v0305820.1
– PREDICTED: phospholipase D epsilon-like [Glycine max] gi|356556716|ref|XP_003546669.1|
Domains
18
Lj3g3v2693180.1
–
Domains
5
Lj3g3v2693190.1
– PREDICTED: phospholipase D epsilon-like [Glycine max] gi|356528853|ref|XP_003533012.1|
Domains
7
Lj4g3v2690740.1
– PREDICTED: phospholipase D delta-like [Cicer arietinum] gi|502140380|ref|XP_004504195.1|
Domains
5
Lj5g3v1500430.1
– PREDICTED: phospholipase D p1-like, partial [Cicer arietinum] gi|502117952|ref|XP_004496027.1|
Domains
21
Lj6g3v1491480.1
– PREDICTED: phospholipase D p1-like [Glycine max] gi|356556110|ref|XP_003546370.1|
Domains
17
Lj6g3v1491490.1
– PREDICTED: phospholipase D p1-like isoform X2 [Cicer arietinum] gi|502085034|ref|XP_004487820.1|
Domains
13
LotjaGi1g1v0384000.1
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|O04865|PLDA1_VIGUN Phospholipase D alpha 1; TrEMBL-Plants: tr|G7JB26|G7JB26_MEDTR Phospholipase D; Found in the gene: LotjaGi1g1v0384000
Domains
21
LotjaGi1g1v0384000.2
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|P86387|PLDA1_CARPA Phospholipase D alpha 1; TrEMBL-Plants: tr|G7JB30|G7JB30_MEDTR Phospholipase D; Found in the gene: LotjaGi1g1v0384000
Domains
20
LotjaGi1g1v0384000.3
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|O04865|PLDA1_VIGUN Phospholipase D alpha 1; TrEMBL-Plants: tr|G7JB26|G7JB26_MEDTR Phospholipase D; Found in the gene: LotjaGi1g1v0384000
Domains
21
LotjaGi1g1v0384000.4
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|P86387|PLDA1_CARPA Phospholipase D alpha 1; TrEMBL-Plants: tr|G7JB30|G7JB30_MEDTR Phospholipase D; Found in the gene: LotjaGi1g1v0384000
Domains
20
LotjaGi1g1v0384000.5
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|P86387|PLDA1_CARPA Phospholipase D alpha 1; TrEMBL-Plants: tr|G7JB30|G7JB30_MEDTR Phospholipase D; Found in the gene: LotjaGi1g1v0384000
Domains
20
LotjaGi1g1v0432500.1
– Phospholipase D; TAIR: AT4G35790.2 phospholipase D delta; Swiss-Prot: sp|Q9C5Y0|PLDD1_ARATH Phospholipase D delta; TrEMBL-Plants: tr|I1JSY8|I1JSY8_SOYBN Phospholipase D; Found in the gene: LotjaGi1g1v0432500
Domains
21
LotjaGi1g1v0432500.2
– Phospholipase D; TAIR: AT4G35790.1 phospholipase D delta; Swiss-Prot: sp|Q9C5Y0|PLDD1_ARATH Phospholipase D delta; TrEMBL-Plants: tr|A0A151TCK8|A0A151TCK8_CAJCA Phospholipase D; Found in the gene: LotjaGi1g1v0432500
Domains
21
LotjaGi1g1v0466900.1
– Phospholipase D; TAIR: AT2G42010.1 phospholipase D beta 1; Swiss-Prot: sp|P93733|PLDB1_ARATH Phospholipase D beta 1; TrEMBL-Plants: tr|I1JDQ3|I1JDQ3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0466900
Domains
20
LotjaGi1g1v0466900.2
– Phospholipase D; TAIR: AT2G42010.1 phospholipase D beta 1; Swiss-Prot: sp|P93733|PLDB1_ARATH Phospholipase D beta 1; TrEMBL-Plants: tr|I1JDQ3|I1JDQ3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0466900
Domains
20
LotjaGi1g1v0466900.3
– Phospholipase D; TAIR: AT2G42010.1 phospholipase D beta 1; Swiss-Prot: sp|P93733|PLDB1_ARATH Phospholipase D beta 1; TrEMBL-Plants: tr|I1JDQ3|I1JDQ3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0466900
Domains
20
LotjaGi2g1v0377200.1
– Phospholipase D; TAIR: AT4G35790.2 phospholipase D delta; Swiss-Prot: sp|Q9C5Y0|PLDD1_ARATH Phospholipase D delta; TrEMBL-Plants: tr|A0A1J7HDZ2|A0A1J7HDZ2_LUPAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0377200
Domains
21
LotjaGi2g1v0430200.1
– Phospholipase D; TAIR: AT2G42010.1 phospholipase D beta 1; Swiss-Prot: sp|P93733|PLDB1_ARATH Phospholipase D beta 1; TrEMBL-Plants: tr|I1JA23|I1JA23_SOYBN Phospholipase D; Found in the gene: LotjaGi2g1v0430200
Domains
23
LotjaGi3g1v0009200.1
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|O04865|PLDA1_VIGUN Phospholipase D alpha 1; TrEMBL-Plants: tr|I1M5T2|I1M5T2_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0009200
Domains
21
LotjaGi3g1v0009200.2
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|O04865|PLDA1_VIGUN Phospholipase D alpha 1; TrEMBL-Plants: tr|I1M5T2|I1M5T2_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0009200
Domains
21
LotjaGi3g1v0024600.1
– Phospholipase D; TAIR: AT1G55180.1 phospholipase D alpha 4; Swiss-Prot: sp|Q9C888|PLDA4_ARATH Phospholipase D alpha 4; TrEMBL-Plants: tr|I1MCY6|I1MCY6_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0024600
Domains
17
LotjaGi3g1v0024600.2
– Phospholipase D; TAIR: AT1G55180.1 phospholipase D alpha 4; Swiss-Prot: sp|Q9C888|PLDA4_ARATH Phospholipase D alpha 4; TrEMBL-Plants: tr|I1MCY6|I1MCY6_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0024600
Domains
17
LotjaGi3g1v0024600.3
– Phospholipase D; TAIR: AT1G55180.1 phospholipase D alpha 4; Swiss-Prot: sp|Q9C888|PLDA4_ARATH Phospholipase D alpha 4; TrEMBL-Plants: tr|I1MCY6|I1MCY6_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0024600
Domains
17
LotjaGi3g1v0024600.4
– Phospholipase D; TAIR: AT1G55180.2 phospholipase D alpha 4; Swiss-Prot: sp|Q9C888|PLDA4_ARATH Phospholipase D alpha 4; TrEMBL-Plants: tr|I1MCY6|I1MCY6_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0024600
Domains
12
LotjaGi3g1v0357200.1
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|O04865|PLDA1_VIGUN Phospholipase D alpha 1; TrEMBL-Plants: tr|G7JI50|G7JI50_MEDTR Phospholipase D; Found in the gene: LotjaGi3g1v0357200
Domains
21
LotjaGi3g1v0357200.2
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|O04865|PLDA1_VIGUN Phospholipase D alpha 1; TrEMBL-Plants: tr|I1KVD8|I1KVD8_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0357200
Domains
21
LotjaGi3g1v0357200.3
– Phospholipase D; TAIR: AT3G15730.1 phospholipase D alpha 1; Swiss-Prot: sp|O04865|PLDA1_VIGUN Phospholipase D alpha 1; TrEMBL-Plants: tr|G7JI50|G7JI50_MEDTR Phospholipase D; Found in the gene: LotjaGi3g1v0357200
Domains
21
LotjaGi3g1v0374800.1
– Phospholipase D; TAIR: AT2G42010.1 phospholipase D beta 1; Swiss-Prot: sp|P93733|PLDB1_ARATH Phospholipase D beta 1; TrEMBL-Plants: tr|A0A1J7HNQ1|A0A1J7HNQ1_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0374800
Domains
20
LotjaGi3g1v0426100.1
– Phospholipase D; TAIR: AT1G55180.1 phospholipase D alpha 4; Swiss-Prot: sp|Q9C888|PLDA4_ARATH Phospholipase D alpha 4; TrEMBL-Plants: tr|K7L7M9|K7L7M9_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0426100
Domains
19
LotjaGi3g1v0426100.2
– Phospholipase D; TAIR: AT1G55180.2 phospholipase D alpha 4; Swiss-Prot: sp|Q9C888|PLDA4_ARATH Phospholipase D alpha 4; TrEMBL-Plants: tr|K7L7N0|K7L7N0_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0426100
Domains
19
LotjaGi3g1v0426100.3
– Phospholipase D; TAIR: AT1G55180.2 phospholipase D alpha 4; Swiss-Prot: sp|Q9C888|PLDA4_ARATH Phospholipase D alpha 4; TrEMBL-Plants: tr|K7L7N0|K7L7N0_SOYBN Phospholipase D; Found in the gene: LotjaGi3g1v0426100
Domains
19
LotjaGi4g1v0387800.1
– Phospholipase D; TAIR: AT4G35790.2 phospholipase D delta; Swiss-Prot: sp|Q9C5Y0|PLDD1_ARATH Phospholipase D delta; TrEMBL-Plants: tr|I1K497|I1K497_SOYBN Phospholipase D; Found in the gene: LotjaGi4g1v0387800
Domains
23
LotjaGi5g1v0226900.1
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|V7BGF2|V7BGF2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0226900
Domains
23
LotjaGi6g1v0252900.1
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|I1MGP5|I1MGP5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0252900
Domains
22
LotjaGi6g1v0252900.2
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|A0A0B2QY87|A0A0B2QY87_GLYSO Phospholipase D p1; Found in the gene: LotjaGi6g1v0252900
Domains
22
LotjaGi6g1v0252900.3
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|A0A0B2QY87|A0A0B2QY87_GLYSO Phospholipase D p1; Found in the gene: LotjaGi6g1v0252900
Domains
22

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 1.89