Domain Predictions — View

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IPR016301

Source: InterPro

Description

IPR016301 is a Phosphoribosylaminoimidazole carboxylase, fungi/plant.

<p>The novo purine biosynthesis proceeds by two divergent paths. In bacteria, yeasts, and plants, 5-aminoimidazole ribonucleotide (AIR) is converted to 4-carboxy-AIR (CAIR) by two enzymes: N5-carboxy-AIR (N5-CAIR) synthetase (PurK) and N5-CAIR mutase (class I PurE). In animals, the conversion of AIR to CAIR requires a single enzyme, AIR carboxylase (class II PurE) [[cite:PUB00065601]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0004638 View details of GO:0004638 AmiGO InterPro QuickGO	Molecular function	Phosphoribosylaminoimidazole carboxylase activity	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2).	Subterm of GO:0016831
GO:0006189 View details of GO:0006189 AmiGO InterPro QuickGO	Biological process	'de novo' IMP biosynthetic process	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.	Subterm of GO:0006188

Associated Lotus transcripts 2

Transcript	Name	Description	Predicted domains	Domain count
Lj0g3v0078859.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: phosphoribosylaminoimidazole carboxylase, chloroplastic-like [Glycine max] gi\|356535191\|ref\|XP_003536132.1\|	Domains G3DSA:3.30.1490.20 G3DSA:3.30.470.20 G3DSA:3.40.50.20 G3DSA:3.40.50.7700 IPR000031 IPR003135 IPR005875 IPR011054 IPR011761 IPR013815 IPR013816 IPR016185 IPR016301 IPR033747 MF_01928 MF_01929 PF00731 PF02222 PIRSF001340 PS50975 PTHR11609 PTHR11609:SF5 SM01001 SSF51246 SSF52255 SSF52440 SSF56059 TIGR01161 TIGR01162 mobidb-lite	30
LotjaGi5g1v0211000.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Formate-dependent phosphoribosylglycinamide formyltransferase; TAIR: AT2G37690.1 phosphoribosylaminoimidazole carboxylase, putative / AIR carboxylase; Swiss-Prot: sp\|P55195\|PUR6_VIGAC Phosphoribosylaminoimidazole carboxylase, chloroplastic; TrEMBL-Plants: tr\|K7LJS8\|K7LJS8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0211000	Domains G3DSA:3.30.1490.20 G3DSA:3.30.470.20 G3DSA:3.40.50.20 G3DSA:3.40.50.7700 IPR000031 IPR003135 IPR005875 IPR011054 IPR011761 IPR013815 IPR016185 IPR016301 IPR033747 IPR035893 IPR040686 MF_01928 MF_01929 PF00731 PF02222 PF17769 PIRSF001340 PS50975 PTHR11609 PTHR11609:SF5 SM01001 SSF51246 SSF52255 SSF52440 SSF56059 TIGR01161 TIGR01162 mobidb-lite	32

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
mobidb-lite	MobiDBLite	1	50.00