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IPR018079 is a Small ribosomal subunit protein uS4, conserved site.
<p>Ribosomal protein uS4 is one of the proteins from the small ribosomal subunit. In Escherichia coli, uS4 is known to bind directly to 16S ribosomal RNA. Mutations in uS4 have been shown to increase translational error frequencies. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [[cite:PUB00004390]], groups:</p> <ul> <li>Eubacterial uS4.</li> <li>Algal and plant chloroplast uS4.</li> <li>Cyanelle uS4.</li> <li>Archaebacterial uS4.</li> <li>Mammalian uS4 (known as S9).</li> <li>Yeast YS11 (SUP46).</li> <li>Marchantia polymorpha (Liverwort) mitochondrial uS4.</li> <li>Dictyostelium discoideum (Slime mold) rp1024.</li> <li>Yeast protein NAM9 [[cite:PUB00003681]]. NAM9 has been characterised as a suppressor for ochre mutations in mitochondrial DNA. It could be a ribosomal protein that acts as a suppressor by decreasing translation accuracy.</li> </ul> <p>uS4 is a protein of 171 to 205 amino-acid residues (except for NAM9 which is much larger).</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | RRNA binding | Interacting selectively and non-covalently with ribosomal RNA. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Ribosomal protein S4 [Lotus japonicus] gi|13518426|ref|NP_084786.1| | 24 | ||
| – | PREDICTED: 40S ribosomal protein S9-2-like [Glycine max] gi|356562820|ref|XP_003549666.1| | 15 | ||
| – | PREDICTED: 40S ribosomal protein S9-2-like [Cicer arietinum] gi|502152082|ref|XP_004508755.1| | 18 | ||
| – | 30S ribosomal protein S4; TAIR: AT5G39850.1 Ribosomal protein S4; Swiss-Prot: sp|Q9FLF0|RS92_ARATH 40S ribosomal protein S9-2; TrEMBL-Plants: tr|I3T2G7|I3T2G7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0218000 | 19 | ||
| – | 30S ribosomal protein S4; TAIR: AT5G39850.1 Ribosomal protein S4; Swiss-Prot: sp|Q9FLF0|RS92_ARATH 40S ribosomal protein S9-2; TrEMBL-Plants: tr|V7CDF1|V7CDF1_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0249100 | 19 | ||
| – | 30S ribosomal protein S4; TAIR: AT5G39850.1 Ribosomal protein S4; Swiss-Prot: sp|Q9FLF0|RS92_ARATH 40S ribosomal protein S9-2; TrEMBL-Plants: tr|V7CDF1|V7CDF1_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0249100 | 19 | ||
| – | 30S ribosomal protein S4; TAIR: AT5G39850.1 Ribosomal protein S4; Swiss-Prot: sp|Q9FLF0|RS92_ARATH 40S ribosomal protein S9-2; TrEMBL-Plants: tr|A0A0B2SUR7|A0A0B2SUR7_GLYSO 40S ribosomal protein S9-2; Found in the gene: LotjaGi4g1v0249100 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00165 | CDD | 1 | 14.29 |