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IPR021139 is a NYN domain.
<p>This NYN domain is found in Meiosis regulator and mRNA stability factor 1 (MARF1, also known as limkain-b1) [[cite:PUB00056072], [cite:PUB00098862]] and some bacterial sequences. The NYN domains are found in the eukaryotic proteins typified by the Nedd4-binding protein 1 and the bacterial YacP-like proteins. The NYN (for Nedd4-BP1, YacP-like Nuclease) domain shares a common protein fold with two other previously characterised groups of nucleases, namely the PIN (PilT N-terminal) and FLAP/5' --> 3' exonuclease superfamilies. These proteins share a common set of 4 acidic conserved residues that are predicted to constitute their active site. Based on the conservation of the acidic residues and structural elements it has been suggested that PIN and NYN domains are likely to bind only a single metal ion, unlike the FLAP/5' --> 3' exonuclease superfamily, which binds two metal ions [[cite:PUB00056584]]. Based on conserved gene neighbourhoods the bacterial members are likely to be components of the processome/degradosome that process tRNAs or ribosomal RNAs.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Limkain-b1 [Medicago truncatula] gi|357511719|ref|XP_003626148.1| | 13 | ||
| – | Limkain-b1 [Medicago truncatula] gi|357464505|ref|XP_003602534.1| | 13 | ||
| – | Limkain-b1 [Medicago truncatula] gi|357511719|ref|XP_003626148.1| | 9 | ||
| – | Zinc finger family protein [Theobroma cacao] gi|508777217|gb|EOY24473.1| | 12 | ||
| – | Zinc finger family protein [Theobroma cacao] gi|508777217|gb|EOY24473.1| | 12 | ||
| – | Meiosis arrest female protein 1; TAIR: AT5G09840.1 Putative endonuclease or glycosyl hydrolase; Swiss-Prot: sp|Q9Y4F3|MARF1_HUMAN Meiosis arrest female protein 1; TrEMBL-Plants: tr|A0A1J7GRS8|A0A1J7GRS8_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0315300 | 13 | ||
| – | Meiosis arrest female protein 1; TAIR: AT3G62200.1 Putative endonuclease or glycosyl hydrolase; Swiss-Prot: sp|E1BZ85|MARF1_CHICK Meiosis arrest female protein 1 homolog; TrEMBL-Plants: tr|I1NBN1|I1NBN1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0751100 | 7 | ||
| – | Zinc finger family protein; TAIR: AT4G12240.1 zinc finger (C2H2 type) family protein; Swiss-Prot: sp|Q9HBE1|PATZ1_HUMAN POZ-, AT hook-, and zinc finger-containing protein 1; TrEMBL-Plants: tr|A0A0L9T4Z6|A0A0L9T4Z6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0500700 | 12 | ||
| – | Meiosis arrest female protein 1-like protein; TAIR: AT2G15560.1 Putative endonuclease or glycosyl hydrolase; Swiss-Prot: sp|Q8BJ34|MARF1_MOUSE Meiosis arrest female protein 1; TrEMBL-Plants: tr|I1JDZ7|I1JDZ7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0075500 | 13 | ||
| – | Meiosis arrest female protein 1-like protein; TAIR: AT2G15560.1 Putative endonuclease or glycosyl hydrolase; Swiss-Prot: sp|Q8BJ34|MARF1_MOUSE Meiosis arrest female protein 1; TrEMBL-Plants: tr|I1JDZ7|I1JDZ7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0075500 | 13 | ||
| – | Meiosis arrest female protein 1-like protein; TAIR: AT2G15560.1 Putative endonuclease or glycosyl hydrolase; Swiss-Prot: sp|Q8BJ34|MARF1_MOUSE Meiosis arrest female protein 1; TrEMBL-Plants: tr|I1JDZ7|I1JDZ7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0075500 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 9.09 |