Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR024049 is a eRF1, domain 1.
<p>The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known [[cite:PUB00007747]]. The overall shape and dimensions of eRF1 resemble a tRNA molecule with domains 1, 2, and 3 of eRF1 corresponding to the anticodon loop, aminoacyl acceptor stem, and T stem of a tRNA molecule, respectively. The position of the essential GGQ motif at an exposed tip of domain 2 suggests that the Gln residue coordinates a water molecule to mediate the hydrolytic activity at the peptidyl transferase centre. A conserved groove on domain 1 is proposed to form the codon recognition site [[cite:PUB00007747]].</p> <p>This entry represents the first domain of eRF1.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: eukaryotic peptide chain release factor subunit 1-3 [Vitis vinifera] gi|225460446|ref|XP_002271656.1| | 19 | ||
| – | PREDICTED: eukaryotic peptide chain release factor subunit 1-3-like [Cicer arietinum] gi|502106984|ref|XP_004493119.1| | 19 | ||
| – | PREDICTED: eukaryotic peptide chain release factor subunit 1-3-like [Glycine max] gi|356531058|ref|XP_003534095.1| | 19 | ||
| – | PREDICTED: eukaryotic peptide chain release factor subunit 1-3-like [Glycine max] gi|356559518|ref|XP_003548046.1| | 6 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|I3T2R1|I3T2R1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0637500 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|I3T2R1|I3T2R1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0637500 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|I3T2R1|I3T2R1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0637500 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|I3T2R1|I3T2R1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0637500 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|I1L3W8|I1L3W8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0182000 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|I1L3W8|I1L3W8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0182000 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|A0A0R0I9D1|A0A0R0I9D1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0182000 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT1G12920.1 eukaryotic release factor 1-2; Swiss-Prot: sp|Q9LPV8|ERF1Y_ARATH Eukaryotic peptide chain release factor subunit 1-2; TrEMBL-Plants: tr|F6I3Y5|F6I3Y5_VITVI Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0218100 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|A0A0L9VIQ2|A0A0L9VIQ2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0015400 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|A0A0L9VIQ2|A0A0L9VIQ2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0015400 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|A0A0L9VIQ2|A0A0L9VIQ2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0015400 | 20 | ||
| – | Eukaryotic peptide chain release factor subunit 1-1; TAIR: AT3G26618.1 eukaryotic release factor 1-3; Swiss-Prot: sp|P35614|ERF1Z_ARATH Eukaryotic peptide chain release factor subunit 1-3; TrEMBL-Plants: tr|A0A0L9VIQ2|A0A0L9VIQ2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0015400 | 20 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR03676 | TIGRFAM | 1 | 6.25 |