Domain Predictions — View

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IPR025709

Source: InterPro

Description

IPR025709 is a Leucyl-tRNA synthetase, editing domain.

<p>This entry represents the editing domain (known as CP1 domain) of Leucyl-tRNA synthetase ([ec:6.1.1.4]), which hydrolyses mischarged tRNALeu. In the case of Leucyl-tRNA synthetase, the β-strands that link the CP1 domain to the aminoacylation core of the protein are also required for editing activity [[cite:PUB00057909]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0002161 View details of GO:0002161 AmiGO InterPro QuickGO	Molecular function	Aminoacyl-tRNA editing activity	The hydrolysis of an incorrectly aminoacylated tRNA.	Subterm of GO:0052689 GO:0140101
GO:0006418 View details of GO:0006418 AmiGO InterPro QuickGO	Biological process	TRNA aminoacylation for protein translation	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.	Subterm of GO:0043039 Part of GO:0006412

Associated Lotus transcripts 6

Transcript	Name	Description	Predicted domains	Domain count
Lj4g3v0134610.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: leucyl-tRNA synthetase-like [Glycine max] gi\|356522021\|ref\|XP_003529648.1\|	Domains G3DSA:3.40.50.620 G3DSA:3.90.740.10 IPR002300 IPR002302 IPR009008 IPR014729 IPR025709 PF00133 PF13603 PR00985 PTHR11946 PTHR11946:SF7 SSF50677 SSF52374	14
Lj4g3v0134610.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: leucyl-tRNA synthetase-like [Glycine max] gi\|356522021\|ref\|XP_003529648.1\|	Domains Coil G3DSA:1.10.730.10 G3DSA:3.40.50.620 G3DSA:3.90.740.10 IPR001412 IPR002300 IPR002302 IPR009008 IPR009080 IPR013155 IPR014729 IPR015413 IPR025709 MF_00049_B NON_CYTOPLASMIC_DOMAIN PF00133 PF08264 PF09334 PF13603 PR00985 PS00178 PTHR11946 PTHR11946:SF7 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF47323 SSF50677 SSF52374 SignalP-TM_GRAM_POSITIVE TIGR00396 cd00812 cd07958 mobidb-lite	35
Lj4g3v0134610.3 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	PREDICTED: leucyl-tRNA synthetase-like [Glycine max] gi\|356522021\|ref\|XP_003529648.1\|	Domains G3DSA:1.10.730.10 G3DSA:3.40.50.620 G3DSA:3.90.740.10 IPR001412 IPR002300 IPR002302 IPR009008 IPR009080 IPR013155 IPR014729 IPR015413 IPR025709 MF_00049_B NON_CYTOPLASMIC_DOMAIN PF00133 PF08264 PF09334 PF13603 PR00985 PS00178 PTHR11946 PTHR11946:SF7 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF47323 SSF50677 SSF52374 SignalP-TM_GRAM_POSITIVE TIGR00396 cd00812 cd07958 mobidb-lite	34
LotjaGi4g1v0011900.1 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Leucine--tRNA ligase; TAIR: AT4G04350.1 tRNA synthetase class I (I, L, M and V) family protein; Swiss-Prot: sp\|Q9XEA0\|SYLM_ARATH Leucine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr\|G7JJA8\|G7JJA8_MEDTR Leucyl-tRNA synthetase; Found in the gene: LotjaGi4g1v0011900	Domains G3DSA:1.10.730.10 G3DSA:2.30.210.10 G3DSA:3.10.20.590 G3DSA:3.40.50.620 G3DSA:3.90.740.10 IPR001412 IPR002300 IPR002302 IPR009008 IPR009080 IPR013155 IPR014729 IPR015413 IPR025709 MF_00049_B NON_CYTOPLASMIC_DOMAIN PF00133 PF08264 PF09334 PF13603 PR00985 PS00178 PTHR43740 PTHR43740:SF6 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF47323 SSF50677 SSF52374 SignalP-TM TIGR00396 cd00812 cd07958	35
LotjaGi4g1v0011900.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Leucine--tRNA ligase; TAIR: AT4G04350.1 tRNA synthetase class I (I, L, M and V) family protein; Swiss-Prot: sp\|Q9XEA0\|SYLM_ARATH Leucine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr\|G7JJA8\|G7JJA8_MEDTR Leucyl-tRNA synthetase; Found in the gene: LotjaGi4g1v0011900	Domains G3DSA:1.10.730.10 G3DSA:2.30.210.10 G3DSA:3.10.20.590 G3DSA:3.40.50.620 G3DSA:3.90.740.10 IPR001412 IPR002300 IPR002302 IPR009008 IPR009080 IPR013155 IPR014729 IPR015413 IPR025709 MF_00049_B NON_CYTOPLASMIC_DOMAIN PF00133 PF08264 PF09334 PF13603 PR00985 PS00178 PTHR43740 PTHR43740:SF6 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SSF47323 SSF50677 SSF52374 SignalP-TM TIGR00396 cd00812 cd07958	35
LotjaGi4g1v0011900.3 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Leucine--tRNA ligase; TAIR: AT4G04350.1 tRNA synthetase class I (I, L, M and V) family protein; Swiss-Prot: sp\|Q9XEA0\|SYLM_ARATH Leucine--tRNA ligase, chloroplastic/mitochondrial; TrEMBL-Plants: tr\|I1KNG6\|I1KNG6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0011900	Domains G3DSA:1.10.730.10 G3DSA:2.30.210.10 G3DSA:3.10.20.590 G3DSA:3.40.50.620 G3DSA:3.90.740.10 IPR001412 IPR002300 IPR002302 IPR009008 IPR009080 IPR013155 IPR014729 IPR015413 IPR025709 MF_00049_B PF00133 PF08264 PF09334 PF13603 PR00985 PS00178 PTHR43740 PTHR43740:SF6 SSF47323 SSF50677 SSF52374 TIGR00396 cd00812 cd07958	29

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
cd07958	CDD	1	16.67