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IPR031322 is a Shikimate kinase/gluconokinase.
<p>Shikimate kinase ([ec:2.7.1.71]) catalyses the fifth step in the biosynthesis of aromatic amino acids from chorismate (the so-called shikimate pathway) [[cite:PUB00001125]]. The enzyme catalyses the following reaction:</p> <p> <reaction> ATP + shikimate = ADP + shikimate-3-phosphate </reaction> </p> <p>The protein is found in bacteria (gene aroK or aroL), plants and fungi (where it is part of a multifunctional enzyme that catalyses five consecutive steps in this pathway). In 1994, the 3D structure of shikimate kinase was predicted to be very close to that of adenylate kinase, suggesting a functional similarity as well as an evolutionary relationship [[cite:PUB00005018]]. This prediction has since been confirmed experimentally. The protein is reported to possess an α/β fold, consisting of a central sheet of five parallel β-strands flanked by α-helices. Such a topology is very similar to that of adenylate kinase [[cite:PUB00003386]].</p> <p>The N terminus of threonine synthase-like 1 from metazoan shares protein sequence similarity with shikimate kinase and is included in this entry. However, their functions may be different.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: shikimate kinase, chloroplastic-like [Glycine max] gi|356525535|ref|XP_003531380.1| | 13 | ||
| – | PREDICTED: thermosensitive gluconokinase-like isoform X2 [Cicer arietinum] gi|502154827|ref|XP_004509854.1| | 7 | ||
| – | PREDICTED: shikimate kinase, chloroplastic [Glycine max] gi|356498875|ref|XP_003518273.1| | 11 | ||
| – | PREDICTED: shikimate kinase, chloroplastic [Glycine max] gi|356498875|ref|XP_003518273.1| | 11 | ||
| – | PREDICTED: shikimate kinase, chloroplastic-like [Glycine max] gi|356525535|ref|XP_003531380.1| | 13 | ||
| – | Shikimate kinase-like protein [Medicago truncatula] gi|357485087|ref|XP_003612831.1| | 14 | ||
| – | Shikimate kinase; TAIR: AT3G26900.1 shikimate kinase like 1; Swiss-Prot: sp|Q9LW20|SKL1_ARATH Probable inactive shikimate kinase like 1, chloroplastic; TrEMBL-Plants: tr|I3STA6|I3STA6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0208500 | 12 | ||
| – | Shikimate kinase; TAIR: AT2G21940.4 shikimate kinase 1; Swiss-Prot: sp|Q00497|SK_SOLLC Shikimate kinase, chloroplastic; TrEMBL-Plants: tr|I3SYZ9|I3SYZ9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0311800 | 13 | ||
| – | Shikimate kinase; TAIR: AT2G21940.4 shikimate kinase 1; Swiss-Prot: sp|Q00497|SK_SOLLC Shikimate kinase, chloroplastic; TrEMBL-Plants: tr|I3SYZ9|I3SYZ9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0311800 | 13 | ||
| – | Shikimate kinase; TAIR: AT2G35500.1 shikimate kinase like 2; Swiss-Prot: sp|O82290|SKL2_ARATH Probable inactive shikimate kinase like 2, chloroplastic; TrEMBL-Plants: tr|I3RZR1|I3RZR1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0354400 | 13 | ||
| – | Gluconokinase; TAIR: AT2G16790.3 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q5T6J7|GNTK_HUMAN Probable gluconokinase; TrEMBL-Plants: tr|K7MRW8|K7MRW8_SOYBN Gluconokinase; Found in the gene: LotjaGi4g1v0163100 | 10 | ||
| – | Shikimate kinase; TAIR: AT2G16790.2 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|B0BML1|GNTK_XENTR Probable gluconokinase; TrEMBL-Plants: tr|I1N1E4|I1N1E4_SOYBN Gluconokinase; Found in the gene: LotjaGi4g1v0163100 | 11 | ||
| – | Shikimate kinase; TAIR: AT2G21940.4 shikimate kinase 1; Swiss-Prot: sp|Q9SJ05|SK1_ARATH Shikimate kinase 1, chloroplastic; TrEMBL-Plants: tr|I3SSP1|I3SSP1_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0403000 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00464 | CDD | 1 | 7.69 |