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IPR031329 is a Neutral/alkaline non-lysosomal ceramidase, N-terminal.
<p>This entry represents the N-terminal domain of a group of neutral/alkaline ceramidases found in both bacteria and eukaryotes [[cite:PUB00007996], [cite:PUB00007997], [cite:PUB00007998]]. The EC classification is ([ec:3.5.1.23]). The enzyme hydrolyses ceramide to generate sphingosine and fatty acid. The enzyme plays a regulatory role in a variety of physiological events in eukaryotes and also functions as an exotoxin in particular bacteria. This N-terminal domain carries two metal-binding sites, the first for Zn2+ residing within the domain, and the second, for Mg2+/Ca2+ lying at the interface between the two domains [[cite:PUB00075611]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: neutral ceramidase-like [Cicer arietinum] gi|502134043|ref|XP_004501980.1| | 5 | ||
| – | PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1| | 13 | ||
| – | PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1| | 11 | ||
| – | PREDICTED: neutral ceramidase-like [Cicer arietinum] gi|502099766|ref|XP_004491555.1| | 8 | ||
| – | PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1| | 11 | ||
| – | PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1| | 13 | ||
| – | Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|G7K4V4|G7K4V4_MEDTR Neutral/alkaline non-lysosomal ceramidase; Found in the gene: LotjaGi1g1v0010900 | 9 | ||
| – | Neutral ceramidase; TAIR: AT1G07380.2 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|G7K4V4|G7K4V4_MEDTR Neutral/alkaline non-lysosomal ceramidase; Found in the gene: LotjaGi1g1v0010900 | 15 | ||
| – | Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|G7K4V4|G7K4V4_MEDTR Neutral/alkaline non-lysosomal ceramidase; Found in the gene: LotjaGi1g1v0010900 | 15 | ||
| – | Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|K7MQD2|K7MQD2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0135100 | 15 | ||
| – | Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q0JL46|NCASE_ORYSJ Neutral ceramidase; TrEMBL-Plants: tr|A0A151UAA4|A0A151UAA4_CAJCA Neutral ceramidase; Found in the gene: LotjaGi6g1v0135100 | 9 | ||
| – | Neutral ceramidase; TAIR: AT2G38010.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|A0A0B2S6C2|A0A0B2S6C2_GLYSO Neutral ceramidase; Found in the gene: LotjaGi6g1v0192400 | 9 | ||
| – | Neutral ceramidase; TAIR: AT2G38010.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|I1LW98|I1LW98_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0192400 | 15 | ||
| – | Neutral ceramidase; TAIR: AT2G38010.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|A0A0R0GS00|A0A0R0GS00_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0192400 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SignalP-noTM | SignalP_GRAM_NEGATIVE | 1 | 7.14 |