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IPR006823

Source: InterPro

Description

IPR006823 is a Neutral/alkaline nonlysosomal ceramidase.

<p>This family represents a group of neutral/alkaline ceramidases found in both bacteria and eukaryotes [[cite:PUB00007996], [cite:PUB00007997], [cite:PUB00007998]]. They hydrolyse the sphingolipid ceramide into sphingosine and free fatty acid.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0017040
Molecular function N-acylsphingosine amidohydrolase activity Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.
Subterm of
GO:0046514
Biological process Ceramide catabolic process The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.
Subterm of

Associated Lotus transcripts 14

Transcript Name Description Predicted domains Domain count
Lj0g3v0208009.1
– PREDICTED: neutral ceramidase-like [Cicer arietinum] gi|502134043|ref|XP_004501980.1|
Domains
5
Lj0g3v0212329.1
– PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1|
Domains
13
Lj0g3v0212329.2
– PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1|
Domains
11
Lj2g3v3336140.1
– PREDICTED: neutral ceramidase-like [Cicer arietinum] gi|502099766|ref|XP_004491555.1|
Domains
8
Lj6g3v0635260.1
– PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1|
Domains
11
Lj6g3v0635260.2
– PREDICTED: neutral ceramidase-like [Glycine max] gi|356566222|ref|XP_003551333.1|
Domains
13
LotjaGi1g1v0010900.1
– Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|G7K4V4|G7K4V4_MEDTR Neutral/alkaline non-lysosomal ceramidase; Found in the gene: LotjaGi1g1v0010900
Domains
9
LotjaGi1g1v0010900.6
– Neutral ceramidase; TAIR: AT1G07380.2 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|G7K4V4|G7K4V4_MEDTR Neutral/alkaline non-lysosomal ceramidase; Found in the gene: LotjaGi1g1v0010900
Domains
15
LotjaGi1g1v0010900.7
– Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|G7K4V4|G7K4V4_MEDTR Neutral/alkaline non-lysosomal ceramidase; Found in the gene: LotjaGi1g1v0010900
Domains
15
LotjaGi6g1v0135100.1
– Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|K7MQD2|K7MQD2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0135100
Domains
15
LotjaGi6g1v0135100.2
– Neutral ceramidase; TAIR: AT1G07380.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q0JL46|NCASE_ORYSJ Neutral ceramidase; TrEMBL-Plants: tr|A0A151UAA4|A0A151UAA4_CAJCA Neutral ceramidase; Found in the gene: LotjaGi6g1v0135100
Domains
9
LotjaGi6g1v0192400.1
– Neutral ceramidase; TAIR: AT2G38010.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|A0A0B2S6C2|A0A0B2S6C2_GLYSO Neutral ceramidase; Found in the gene: LotjaGi6g1v0192400
Domains
9
LotjaGi6g1v0192400.2
– Neutral ceramidase; TAIR: AT2G38010.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|I1LW98|I1LW98_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0192400
Domains
15
LotjaGi6g1v0192400.3
– Neutral ceramidase; TAIR: AT2G38010.1 Neutral/alkaline non-lysosomal ceramidase; Swiss-Prot: sp|Q304B9|NCASE_ARATH Neutral ceramidase; TrEMBL-Plants: tr|A0A0R0GS00|A0A0R0GS00_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0192400
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SignalP-noTM SignalP_GRAM_NEGATIVE 1 7.14