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IPR035100 is a Transcription elongation factor, IIS-type.
<p>This group represents transcription elongation factor IIS (TFIIS) and transcription factor S-II homologues from viruses. TFIIS is a component of RNA polymerase II preinitiation complexes, and is required for preinitiation complex assembly and stability [[cite:PUB00042911]]. TFIIS binds to RNA polymerase Pol II, and in stalled and arrested elongation complexes it stimulates the cleavage of the nascent transcript at the 3' end. It enhances the excision of mis-incorporated nucleotides by RNA polymerase II, providing an mRNA proof-reading mechanism during transcription elongation [[cite:PUB00085153]]. Three distinct TFIIS isoforms exist in vertebrates [[cite:PUB00085152]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Transcription elongation factor; TAIR: AT2G38560.1 transcript elongation factor IIS; Swiss-Prot: sp|Q9ZVH8|RDO2_ARATH Transcription elongation factor TFIIS; TrEMBL-Plants: tr|I1JYC9|I1JYC9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0305500 | 32 | ||
– | Transcription elongation factor; TAIR: AT2G38560.1 transcript elongation factor IIS; Swiss-Prot: sp|Q9ZVH8|RDO2_ARATH Transcription elongation factor TFIIS; TrEMBL-Plants: tr|I1JYC9|I1JYC9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0305500 | 32 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 50.00 |