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IPR036372

Source: InterPro

Description

IPR036372 is a BEACH domain superfamily.

<p>BEACH (Beige and Chediak-Higashi) domains, implicated in membrane trafficking, are present in a family of proteins conserved throughout eukaryotes. This group contains human lysosomal trafficking regulator (LYST), LPS-responsive and beige-like anchor (LRBA) and neurobeachin. Disruption of LYST leads to Chediak-Higashi syndrome, characterized by severe immunodeficiency, albinism, poor blood coagulation and neurologic problems. Neurobeachin is a candidate gene linked to autism. LBRA seems to be upregulated in several cancer types. It has been shown that the BEACH domain itself is important for the function of these proteins [[cite:PUB00079623], [cite:PUB00079624], [cite:PUB00079625], [cite:PUB00079626], [cite:PUB00062010], [cite:PUB00075926], [cite:PUB00054617], [cite:PUB00079627]].</p> <p>The BEACH domain is usually followed by a series of WD repeats.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 27

Transcript Name Description Predicted domains Domain count
LotjaGi1g1v0224200.1
– BEACH domain-containing protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|A0A151SN80|A0A151SN80_CAJCA Neurobeachin-like protein 1; Found in the gene: LotjaGi1g1v0224200
Domains
10
LotjaGi1g1v0224200.2
– BEACH domain-containing protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|A0A151SN80|A0A151SN80_CAJCA Neurobeachin-like protein 1; Found in the gene: LotjaGi1g1v0224200
Domains
10
LotjaGi1g1v0313900_LC.1
– BEACH domain-containing protein; TAIR: AT2G45540.2 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|A0A1J7FPD1|A0A1J7FPD1_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0313900_LC
Domains
9
LotjaGi1g1v0344900.1
– BEACH domain-containing protein lvsC; TAIR: AT1G58230.1 binding protein; Swiss-Prot: sp|F4I9T0|BCHB_ARATH BEACH domain-containing protein B; TrEMBL-Plants: tr|A0A0R0K6C6|A0A0R0K6C6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0344900
Domains
43
LotjaGi1g1v0344900.2
– BEACH domain-containing protein lvsC; TAIR: AT1G58230.2 binding protein; Swiss-Prot: sp|F4I9T0|BCHB_ARATH BEACH domain-containing protein B; TrEMBL-Plants: tr|A0A0R0K6C6|A0A0R0K6C6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0344900
Domains
41
LotjaGi1g1v0344900.3
– BEACH domain-containing protein lvsC; TAIR: AT1G58230.2 binding protein; Swiss-Prot: sp|F4I9T0|BCHB_ARATH BEACH domain-containing protein B; TrEMBL-Plants: tr|A0A0R0K6C6|A0A0R0K6C6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0344900
Domains
43
LotjaGi1g1v0344900.4
– BEACH domain-containing protein lvsC; TAIR: AT1G58230.2 binding protein; Swiss-Prot: sp|F4I9T0|BCHB_ARATH BEACH domain-containing protein B; TrEMBL-Plants: tr|A0A0R0K6C6|A0A0R0K6C6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0344900
Domains
29
LotjaGi1g1v0344900.5
– BEACH domain-containing protein lvsC; TAIR: AT1G58230.1 binding protein; Swiss-Prot: sp|F4I9T0|BCHB_ARATH BEACH domain-containing protein B; TrEMBL-Plants: tr|A0A0R0K6C6|A0A0R0K6C6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0344900
Domains
43
LotjaGi1g1v0465300.1
– Beige/BEACH domain protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|G7L1D4|G7L1D4_MEDTR WD-40 repeat protein/beige protein; Found in the gene: LotjaGi1g1v0465300
Domains
30
LotjaGi1g1v0465300.2
– BEACH domain-containing protein; TAIR: AT2G45540.2 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|G7L1D4|G7L1D4_MEDTR WD-40 repeat protein/beige protein; Found in the gene: LotjaGi1g1v0465300
Domains
25
LotjaGi1g1v0465300.3
– BEACH domain-containing protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|A0A0S3RTB2|A0A0S3RTB2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0465300
Domains
27
LotjaGi1g1v0465300.4
– Beige/BEACH domain protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|G7L1D4|G7L1D4_MEDTR WD-40 repeat protein/beige protein; Found in the gene: LotjaGi1g1v0465300
Domains
30
LotjaGi1g1v0686800_LC.1
– BEACH domain-containing protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|I3SY36|I3SY36_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0686800_LC
Domains
12
LotjaGi3g1v0430900.1
– Beige/BEACH domain protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|G7LDJ7|G7LDJ7_MEDTR WD-40 repeat protein/beige protein; Found in the gene: LotjaGi3g1v0430900
Domains
23
LotjaGi3g1v0430900.2
– BEACH domain-containing protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|G7LDJ7|G7LDJ7_MEDTR WD-40 repeat protein/beige protein; Found in the gene: LotjaGi3g1v0430900
Domains
35
LotjaGi3g1v0430900.3
– Beige/BEACH domain protein; TAIR: AT2G45540.1 WD-40 repeat family protein / beige-like protein; Swiss-Prot: sp|F4IG73|BCHC2_ARATH BEACH domain-containing protein C2; TrEMBL-Plants: tr|G7LDJ7|G7LDJ7_MEDTR WD-40 repeat protein/beige protein; Found in the gene: LotjaGi3g1v0430900
Domains
34
LotjaGi5g1v0173300.1
– WD repeat and FYVE domain-containing protein 3; TAIR: AT1G03060.2 BEACH-DOMAIN HOMOLOG A1; Swiss-Prot: sp|F4HZB2|BCHA1_ARATH Protein SPIRRIG; TrEMBL-Plants: tr|I1JF68|I1JF68_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0173300
Domains
33
LotjaGi5g1v0173300.2
– WD repeat and FYVE domain-containing protein 3; TAIR: AT1G03060.1 BEACH-DOMAIN HOMOLOG A1; Swiss-Prot: sp|F4HZB2|BCHA1_ARATH Protein SPIRRIG; TrEMBL-Plants: tr|I1JF68|I1JF68_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0173300
Domains
32
LotjaGi5g1v0173300.3
– WD repeat and FYVE domain-containing protein 3; TAIR: AT1G03060.1 BEACH-DOMAIN HOMOLOG A1; Swiss-Prot: sp|F4HZB2|BCHA1_ARATH Protein SPIRRIG; TrEMBL-Plants: tr|I1JF68|I1JF68_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0173300
Domains
32
LotjaGi5g1v0173300.4
– WD repeat and FYVE domain-containing protein 3; TAIR: AT1G03060.1 BEACH-DOMAIN HOMOLOG A1; Swiss-Prot: sp|F4HZB2|BCHA1_ARATH Protein SPIRRIG; TrEMBL-Plants: tr|I1JF68|I1JF68_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0173300
Domains
32
LotjaGi5g1v0173300.5
– WD repeat and FYVE domain-containing protein 3; TAIR: AT1G03060.1 BEACH-DOMAIN HOMOLOG A1; Swiss-Prot: sp|F4HZB2|BCHA1_ARATH Protein SPIRRIG; TrEMBL-Plants: tr|I1JF68|I1JF68_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0173300
Domains
32
LotjaGi5g1v0173300.6
– WD repeat and FYVE domain-containing protein 3; TAIR: AT1G03060.1 BEACH-DOMAIN HOMOLOG A1; Swiss-Prot: sp|F4HZB2|BCHA1_ARATH Protein SPIRRIG; TrEMBL-Plants: tr|G7ICR2|G7ICR2_MEDTR Beige/BEACH and WD40 domain protein; Found in the gene: LotjaGi5g1v0173300
Domains
34
LotjaGi5g1v0173300.7
– BEACH domain-containing protein; TAIR: AT1G03060.1 BEACH-DOMAIN HOMOLOG A1; Swiss-Prot: sp|F4HZB2|BCHA1_ARATH Protein SPIRRIG; TrEMBL-Plants: tr|A0A0L9TX07|A0A0L9TX07_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0173300
Domains
23
LotjaGi5g1v0309900.2
– Protein kinase family protein; TAIR: AT5G18525.1 protein serine/threonine kinase; Swiss-Prot: sp|F4JY12|GFS12_ARATH Protein GFS12; TrEMBL-Plants: tr|K7N3K0|K7N3K0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0309900
Domains
27
LotjaGi5g1v0309900.3
– Protein kinase family protein; TAIR: AT5G18525.1 protein serine/threonine kinase; Swiss-Prot: sp|F4JY12|GFS12_ARATH Protein GFS12; TrEMBL-Plants: tr|K7N3K0|K7N3K0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0309900
Domains
23
LotjaGi5g1v0309900.4
– Protein kinase family protein; TAIR: AT5G18525.1 protein serine/threonine kinase; Swiss-Prot: sp|F4JY12|GFS12_ARATH Protein GFS12; TrEMBL-Plants: tr|K7N3K0|K7N3K0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0309900
Domains
27
LotjaGi5g1v0309900.5
– Protein kinase family protein; TAIR: AT5G18525.1 protein serine/threonine kinase; Swiss-Prot: sp|F4JY12|GFS12_ARATH Protein GFS12; TrEMBL-Plants: tr|K7N3K0|K7N3K0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0309900
Domains
27

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd06071 CDD 1 3.70