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IPR040023

Source: InterPro

Description

IPR040023 is a WW domain-binding protein 4.

<p>WW domain-binding protein 4 (WBP4; also known as formin-binding protein 21) is a component of the spliceosome, which is involved in pre-mRNA splicing [[cite:PUB00090272]]. It contains a matrin-type zinc finger and two tandem WW domains. It interacts with the splicing factor SIPP1, and its binding and activation of pre-mRNA splicing depend on the WW domains [[cite:PUB00052665]]. This entry also includes zinc finger protein ZOP1 from Arabidopsis thaliana, which is also a pre-mRNA splicing factor that associates with several typical components of the splicing machinery and promotes Pol IV-dependent siRNA accumulation, DNA methylation, and transcriptional silencing [[cite:PUB00085725]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000398
Biological process MRNA splicing, via spliceosome The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi4g1v0071400.1
– U1 small nuclear ribonucleoprotein C; TAIR: AT1G49590.1 C2H2 and C2HC zinc fingers superfamily protein; Swiss-Prot: sp|Q7XA66|ZOP1_ARATH Zinc finger protein ZOP1; TrEMBL-Plants: tr|I3S6A8|I3S6A8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0071400
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00