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GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Damaged DNA binding | Interacting selectively and non-covalently with damaged DNA. | ||
Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | ||
Molecular function | Nucleotidyltransferase activity | Catalysis of the transfer of a nucleotidyl group to a reactant. | ||
Biological process | Error-prone translesion synthesis | The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: DNA repair protein REV1-like isoform X2 [Cicer arietinum] gi|502158837|ref|XP_004511297.1| | 25 | ||
– | PREDICTED: DNA repair protein REV1-like isoform X2 [Cicer arietinum] gi|502158837|ref|XP_004511297.1| | 25 | ||
– | DNA polymerase IV; TAIR: AT5G44750.1 DNA-directed DNA polymerase; Swiss-Prot: sp|A3EWL3|REV1_ARATH DNA repair protein REV1; TrEMBL-Plants: tr|A0A0R0LQ66|A0A0R0LQ66_SOYBN DNA repair protein REV1; Found in the gene: LotjaGi2g1v0461300 | 29 | ||
– | DNA polymerase IV; TAIR: AT5G44750.1 DNA-directed DNA polymerase; Swiss-Prot: sp|A3EWL3|REV1_ARATH DNA repair protein REV1; TrEMBL-Plants: tr|A0A0R0LQ66|A0A0R0LQ66_SOYBN DNA repair protein REV1; Found in the gene: LotjaGi2g1v0461300 | 29 | ||
– | DNA polymerase IV; TAIR: AT5G44750.1 DNA-directed DNA polymerase; Swiss-Prot: sp|A3EWL3|REV1_ARATH DNA repair protein REV1; TrEMBL-Plants: tr|A0A0R0LQ66|A0A0R0LQ66_SOYBN DNA repair protein REV1; Found in the gene: LotjaGi2g1v0461300 | 26 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 20.00 |