Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
Field | Value |
---|---|
Namespace | Biological process |
Short description | Protein import into mitochondrial inner membrane |
Full defintion | The process comprising the import of proteins into the mitochondrion from outside the organelle and their insertion into the mitochondrial inner membrane. The translocase of the outer membrane complex mediates the passage of these proteins across the outer membrane, after which they are guided by either of two inner membrane translocase complexes into their final destination in the inner membrane. |
Subterm of |
The relationship of GO:0045039 with other GO terms.
Relationship type | GO terms |
---|---|
Is a | |
Regulates | n.a. |
Part of | |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:0045039, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
---|---|
GOC | vw |
PMID | Thirty years of protein translocation into mitochondria: unexpectedly complex and still puzzling. Biochim Biophys Acta. 2009 Jan; 1793 (1): 33–41.PMID: 18672008 Mitochondria are essential organelles of the eukaryotic cells that are made by expansion and division of pre-existing mitochondria. The majority of their protein constituents are synthesized in the cytosol. They are transported into and put together within the organelle. This complex process is facilitated by several protein translocases. Here we summarize current knowledge on these sophisticated molecular machines that mediate recognition, transport across membranes and intramitochondrial sorting of many hundreds of mitochondrial proteins. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | Mitochondrial import inner membrane translocase subunit TIM22; TAIR: AT5G55510.1 Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; Swiss-Prot: sp|Q6NKU9|TI223_ARATH Mitochondrial import inner membrane translocase subunit TIM22-3; TrEMBL-Plants: tr|I3T6N2|I3T6N2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0021500 | 2 | ||
– | Mitochondrial import inner membrane translocase subunit TIM22; TAIR: AT5G24650.1 Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; Swiss-Prot: sp|Q6NKU9|TI223_ARATH Mitochondrial import inner membrane translocase subunit TIM22-3; TrEMBL-Plants: tr|I1JYE9|I1JYE9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0302500 | 2 | ||
– | Mitochondrial import inner membrane translocase subunit Tim22; TAIR: AT2G42210.1 Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; Swiss-Prot: sp|O48528|OP163_ARATH Outer envelope pore protein 16-3, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I3T3A7|I3T3A7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0724800 | 2 | ||
– | Mitochondrial import inner membrane translocase subunit Tim22; TAIR: AT2G42210.1 Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; Swiss-Prot: sp|O48528|OP163_ARATH Outer envelope pore protein 16-3, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I3T3A7|I3T3A7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0724800 | 2 | ||
– | Mitochondrial import inner membrane translocase subunit TIM22; TAIR: AT3G10110.1 Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; Swiss-Prot: sp|A2RVP7|TI221_ARATH Mitochondrial import inner membrane translocase subunit TIM22-1; TrEMBL-Plants: tr|I3SGH6|I3SGH6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0542300 | 2 | ||
– | Mitochondrial import inner membrane translocase subunit tim22; TAIR: AT3G62880.1 Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; Swiss-Prot: sp|Q9LZH8|OP164_ARATH Outer envelope pore protein 16-4, chloroplastic; TrEMBL-Plants: tr|I3T2W3|I3T2W3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0250400 | 2 | ||
– | Mitochondrial import inner membrane translocase subunit tim22; TAIR: AT3G62880.1 Mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein; Swiss-Prot: sp|Q9LZH8|OP164_ARATH Outer envelope pore protein 16-4, chloroplastic; TrEMBL-Plants: tr|I3T2W3|I3T2W3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0250400 | 2 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Biological process | Protein import into mitochondrial inner membrane | 1 | 14.29 |