Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

GO:0089701

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description U2AF
Full defintion A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point.
Subterm of

Relationships

The relationship of GO:0089701 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0089701, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

  • Drag and drop nodes to manually position (i.e. fix) them
  • Double click on a node to unfix the node
  • Press Alt and double click to visit the page containing further details of a GO term
  • Right clicking on a node will reveal a context menu

Controls

Force layout

Every force layout is different—we have picked a set of parameters which suits most GO ancestor tree chart well. If you mess something up—don't worry: hitting the "reset view" button above will reset the chart to its default layout.

Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCmah
PMID
The small subunit of the splicing factor U2AF is conserved in fission yeast.Wentz-Hunter K, Potashkin J
Nucleic Acids Res. 1996 May 15; 24 (10): 1849–54.PMID: 8657565

The human splicing factor U2 auxiliary factor (hsU2AF) is comprised of two interacting subunits of 65 and 35 kDa. Previously we identified the Schizosaccharomyces pombe homolog, spU2AF59, of the human large subunit. We have screened a fission yeast cDNA library in search of proteins that interact with spU2AF59 using the yeast two-hybrid system and have identified a homolog of the hsU2AF35 subunit. The S. pombe U2AF small subunit is a single copy gene that encodes a protein which shares 55% amino acid identity and 17% similarity with the human small subunit. Unlike the human protein, the yeast protein lacks an arginine/serine-rich region. The predicted molecular mass of the spU2AF small subunit is 23 kDa. The region of spU2AF59 that interacts with spU2AF23 is similar to the region in which the human small and large subunits interact.

Associated Lotus transcripts 19

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0004639.1
– Zinc finger C-x8-C-x5-C-x3-H type family protein [Theobroma cacao] gi|508786323|gb|EOY33579.1|
GO terms
3
Lj0g3v0180079.1
– Splicing factor U2af subunit isoform 1 [Zea mays] gi|413948479|gb|AFW81128.1|
GO terms
3
Lj0g3v0290279.1
– PREDICTED: zinc finger CCCH domain-containing protein 5-like [Glycine max] gi|356528629|ref|XP_003532902.1|
GO terms
3
Lj0g3v0290279.2
– PREDICTED: zinc finger CCCH domain-containing protein 5-like [Glycine max] gi|356528629|ref|XP_003532902.1|
GO terms
3
Lj0g3v0290329.1
– Zinc finger CCCH domain-containing protein 5 [Arabidopsis thaliana] gi|15218489|ref|NP_172503.1|
GO terms
3
Lj0g3v0290329.2
– U2 auxiliary factor small subunit [Medicago truncatula] gi|140053487|gb|ABO80462.1|
GO terms
3
Lj0g3v0290329.3
– Zinc finger CCCH domain-containing protein 5 [Arabidopsis thaliana] gi|15218489|ref|NP_172503.1|
GO terms
3
Lj0g3v0290349.1
– Zinc finger CCCH domain-containing protein 5 [Arabidopsis thaliana] gi|15218489|ref|NP_172503.1|
GO terms
3
Lj1g3v4694450.1
– PREDICTED: splicing factor U2af small subunit B-like [Glycine max] gi|356505320|ref|XP_003521439.1|
GO terms
3
Lj3g3v1132330.3
– Zinc finger C-x8-C-x5-C-x3-H type family protein [Theobroma cacao] gi|508786323|gb|EOY33579.1|
GO terms
3
Lj3g3v3006550.1
– Zinc finger C-x8-C-x5-C-x3-H type family protein [Theobroma cacao] gi|508786323|gb|EOY33579.1|
GO terms
3
LotjaGi1g1v0680100.1
– Splicing factor U2af small subunit A-like protein; TAIR: AT5G42820.1 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9FMY5|U2AFB_ARATH Splicing factor U2af small subunit B; TrEMBL-Plants: tr|I3SLP5|I3SLP5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0680100
GO terms
3
LotjaGi2g1v0011500.1
– Splicing factor U2af small subunit A; TAIR: AT5G42820.1 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9FMY5|U2AFB_ARATH Splicing factor U2af small subunit B; TrEMBL-Plants: tr|A0A1D1Z0R2|A0A1D1Z0R2_9ARAE Splicing factor U2af small subunit A; Found in the gene: LotjaGi2g1v0011500
GO terms
3
LotjaGi2g1v0011500.2
– Splicing factor U2af small subunit A; TAIR: AT5G42820.1 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9FMY5|U2AFB_ARATH Splicing factor U2af small subunit B; TrEMBL-Plants: tr|A0A1D1Z0R2|A0A1D1Z0R2_9ARAE Splicing factor U2af small subunit A; Found in the gene: LotjaGi2g1v0011500
GO terms
3
LotjaGi3g1v0172600.1
– Splicing factor U2af small subunit A; TAIR: AT5G42820.1 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9ZQW8|U2AFA_ORYSJ Splicing factor U2af small subunit A; TrEMBL-Plants: tr|A0A1J7IB44|A0A1J7IB44_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0172600
GO terms
3
LotjaGi3g1v0481000.1
– Splicing factor U2af small subunit A; TAIR: AT5G42820.1 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9ZQW8|U2AFA_ORYSJ Splicing factor U2af small subunit A; TrEMBL-Plants: tr|A0A1J7IB44|A0A1J7IB44_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0481000
GO terms
3
LotjaGi5g1v0035100.1
– Zinc finger CCCH domain protein, putative; TAIR: AT1G10320.2 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9SY74|C3H5_ARATH Zinc finger CCCH domain-containing protein 5; TrEMBL-Plants: tr|A0A178W6J5|A0A178W6J5_ARATH Uncharacterized protein; Found in the gene: LotjaGi5g1v0035100
GO terms
3
LotjaGi5g1v0035100.2
– Zinc finger CCCH domain protein, putative; TAIR: AT1G10320.2 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9SY74|C3H5_ARATH Zinc finger CCCH domain-containing protein 5; TrEMBL-Plants: tr|A0A178W6J5|A0A178W6J5_ARATH Uncharacterized protein; Found in the gene: LotjaGi5g1v0035100
GO terms
3
LotjaGi5g1v0035100.3
– Zinc finger CCCH domain protein, putative; TAIR: AT1G10320.2 Zinc finger C-x8-C-x5-C-x3-H type family protein; Swiss-Prot: sp|Q9SY74|C3H5_ARATH Zinc finger CCCH domain-containing protein 5; TrEMBL-Plants: tr|A0A178W6J5|A0A178W6J5_ARATH Uncharacterized protein; Found in the gene: LotjaGi5g1v0035100
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0089701
Cellular component U2AF 1 5.26