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Lj6g3v0933510.1

Overview

Field Value
Gene ID Lj6g3v0933510
Transcript ID Lj6g3v0933510.1
Lotus japonicus genome version MG20 v3.0
Description E3 ubiquitin-protein ligase synoviolin [Medicago truncatula] gi|357481129|ref|XP_003610850.1|
Working Lj name n.a.

Sequence information

Domain prediction

Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.

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Domains

Sorting

Prediction algorithm Identifier Start End Length E-value InterPro ID
Phobius 1 7 7
Phobius 1 27 27
PANTHER 1 369 369 1.20E-167
PANTHER 1 369 369 1.20E-167
TMHMM 7 24 18
Phobius 8 19 12
Phobius 20 27 8
Phobius 28 42 15
TMHMM 39 61 23
Phobius 43 60 18
Phobius 61 98 38
Phobius 99 119 21
TMHMM 99 121 23
Phobius 120 138 19
TMHMM 136 158 23
Phobius 139 159 21
Phobius 160 170 11
TMHMM 171 193 23
Phobius 171 195 25
Phobius 196 224 29
TMHMM 224 246 23
Phobius 225 246 22
Phobius 247 549 303
SUPERFAMILY 272 336 65 9.06E-21
Gene3D 281 334 54 3.60E-16
Pfam 291 330 40 6.70E-11
CDD 291 333 43 2.36E-13
ProSiteProfiles 292 330 39 12.622
SMART 292 329 38 7.60E-04
MobiDBLite 340 380 41
PANTHER 484 533 50 1.20E-167
PANTHER 484 533 50 1.20E-167
MobiDBLite 503 549 47

Gene function (GO predictions)

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Cellular component Hrd1p ubiquitin ligase complex A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
Biological process Protein ubiquitination The process in which one or more ubiquitin groups are added to a protein.
Biological process Ubiquitin-dependent ERAD pathway The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
Molecular function Ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.

Expression data

Expression pattern

Expression pattern of Lj6g3v0933510.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.

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Co-expressed genes

A list of the top 25 highly co-expressed genes of Lj6g3v0933510.1, powered by CORGI.

Loading co-expressed genes from the dataset ljgea-geneid. This will take 20–30 seconds to construct.