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IPR001339

Source: InterPro

Description

IPR001339 is a mRNA capping enzyme, adenylation domain.

<p>This entry represents the adenylation domain of the mRNA capping enzyme [[cite:PUB00000947]]. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an RNA 5'-triphosphatase [[cite:PUB00000947]]. Binding of the enzyme to nucleotides is specific to the GMP moiety of GTP. The viral mRNA capping enzyme is a monomer that transfers a GMP cap onto the end of mRNA that terminates with a 5'-diphosphate tail.</p> <p>It contains a catalytic core composed of an adenylation domain and a C-terminal OB-fold domain containing conserved sequence motifs. The adenylation domain binds ATP and contains many active site residues [[cite:PUB00079683], [cite:PUB00029683]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004484
Molecular function MRNA guanylyltransferase activity Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
Subterm of
GO:0006370
Biological process 7-methylguanosine mRNA capping Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
Subterm of

Associated Lotus transcripts 17

Transcript Name Description Predicted domains Domain count
Lj0g3v0256839.1
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356568041|ref|XP_003552222.1|
Domains
19
Lj0g3v0256839.2
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356568041|ref|XP_003552222.1|
Domains
29
Lj1g3v0270180.1
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356570562|ref|XP_003553454.1|
Domains
12
Lj1g3v4419670.1
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356570562|ref|XP_003553454.1|
Domains
20
Lj1g3v4419670.2
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356570562|ref|XP_003553454.1|
Domains
26
Lj1g3v4419670.3
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356570562|ref|XP_003553454.1|
Domains
16
Lj3g3v1603870.1
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356504293|ref|XP_003520931.1|
Domains
22
Lj3g3v1603870.2
– PREDICTED: mRNA-capping enzyme-like [Glycine max] gi|356496154|ref|XP_003516935.1|
Domains
29
LotjaGi1g1v0572100.1
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|K7MTE7|K7MTE7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0572100
Domains
30
LotjaGi1g1v0572100.2
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|K7MTE7|K7MTE7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0572100
Domains
29
LotjaGi1g1v0572100.3
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|A0A0R0FB81|A0A0R0FB81_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0572100
Domains
29
LotjaGi1g1v0572100.4
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|K7MTE7|K7MTE7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0572100
Domains
29
LotjaGi1g1v0728900.1
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|A0A0B2SM84|A0A0B2SM84_GLYSO mRNA-capping enzyme; Found in the gene: LotjaGi1g1v0728900
Domains
27
LotjaGi3g1v0215700.1
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|K7KDH1|K7KDH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0215700
Domains
23
LotjaGi3g1v0215700.2
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|K7K355|K7K355_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0215700
Domains
30
LotjaGi3g1v0215700.3
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|A0A151RAA8|A0A151RAA8_CAJCA mRNA-capping enzyme; Found in the gene: LotjaGi3g1v0215700
Domains
29
LotjaGi3g1v0215700.4
– MRNA-capping enzyme; TAIR: AT3G09100.2 mRNA capping enzyme family protein; Swiss-Prot: sp|O55236|MCE1_MOUSE mRNA-capping enzyme; TrEMBL-Plants: tr|K7K355|K7K355_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0215700
Domains
30

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 5.88