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IPR013032 is a EGF-like, conserved site.
<p>This entry represents a conserved site in the EGF-like domain.</p> <p>A sequence of about thirty to forty amino-acid residues long found in the sequence of epidermal growth factor (EGF) has been shown [[cite:PUB00001555], [cite:PUB00003983], [cite:PUB00004321], [cite:PUB00004609]] to be present, in a more or less conserved form, in a large number of other, mostly animal proteins. The list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied. The functional significance of EGF domains in what appear to be unrelated proteins is not yet clear. However, a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase). The EGF domain includes six cysteine residues which have been shown (in EGF) to be involved in disulphide bonds. The main structure is a two-stranded β-sheet followed by a loop to a C-terminal short two-stranded sheet. Subdomains between the conserved cysteines vary in length.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Exostosin family protein isoform 1 [Theobroma cacao] gi|508717444|gb|EOY09341.1| | 14 | ||
| – | Transmembrane protein 8B [Medicago truncatula] gi|357504417|ref|XP_003622497.1| | 17 | ||
| – | PREDICTED: leishmanolysin-like isoform X1 [Cicer arietinum] gi|502131608|ref|XP_004501040.1| | 20 | ||
| – | PREDICTED: leishmanolysin-like isoform X2 [Cicer arietinum] gi|502131611|ref|XP_004501041.1| | 22 | ||
| – | Leishmanolysin-like peptidase; TAIR: AT5G42620.2 metalloendopeptidase / zinc ion binding protein; Swiss-Prot: sp|Q9VH19|LMLN_DROME Leishmanolysin-like peptidase; TrEMBL-Plants: tr|A0A0B2PA32|A0A0B2PA32_GLYSO Leishmanolysin-like peptidase; Found in the gene: LotjaGi1g1v0417600 | 20 | ||
| – | Leishmanolysin-like peptidase; TAIR: AT5G42620.2 metalloendopeptidase / zinc ion binding protein; Swiss-Prot: sp|Q9VH19|LMLN_DROME Leishmanolysin-like peptidase; TrEMBL-Plants: tr|A0A0B2PA32|A0A0B2PA32_GLYSO Leishmanolysin-like peptidase; Found in the gene: LotjaGi1g1v0417600 | 22 | ||
| – | Vacuolar-sorting receptor-like protein; TAIR: AT2G14740.1 vaculolar sorting receptor 3; Swiss-Prot: sp|P93484|VSR1_PEA Vacuolar-sorting receptor 1; TrEMBL-Plants: tr|A0A151RZ12|A0A151RZ12_CAJCA Vacuolar-sorting receptor 1; Found in the gene: LotjaGi2g1v0460100 | 22 | ||
| – | Transmembrane protein 8B; TAIR: AT2G46060.1 transmembrane protein-like protein; Swiss-Prot: sp|A6NDV4|TMM8B_HUMAN Transmembrane protein 8B; TrEMBL-Plants: tr|A0A151UCT6|A0A151UCT6_CAJCA Transmembrane protein 8B; Found in the gene: LotjaGi3g1v0385400 | 16 | ||
| – | Transmembrane protein 8B; TAIR: AT2G46060.1 transmembrane protein-like protein; Swiss-Prot: sp|A6NDV4|TMM8B_HUMAN Transmembrane protein 8B; TrEMBL-Plants: tr|A0A151UCT6|A0A151UCT6_CAJCA Transmembrane protein 8B; Found in the gene: LotjaGi3g1v0385400 | 11 | ||
| – | Kinase family protein; TAIR: AT1G67000.1 Protein kinase superfamily protein; Swiss-Prot: sp|Q3ECH2|LRL28_ARATH LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.8; TrEMBL-Plants: tr|A0A0R0IJ31|A0A0R0IJ31_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0237200_LC | 8 | ||
| – | Leishmanolysin-like peptidase; TAIR: AT5G42620.2 metalloendopeptidase / zinc ion binding protein; Swiss-Prot: sp|Q29AK2|LMLN_DROPS Leishmanolysin-like peptidase; TrEMBL-Plants: tr|I1MXU3|I1MXU3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0018900 | 21 | ||
| – | Leishmanolysin-like peptidase; TAIR: AT5G42620.2 metalloendopeptidase / zinc ion binding protein; Swiss-Prot: sp|Q29AK2|LMLN_DROPS Leishmanolysin-like peptidase; TrEMBL-Plants: tr|I1MXU3|I1MXU3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0018900 | 23 | ||
| – | Exostosin family protein; TAIR: AT3G57630.1 exostosin family protein; Swiss-Prot: sp|Q6NMM8|F8H_ARATH Probable glucuronoxylan glucuronosyltransferase F8H; TrEMBL-Plants: tr|A0A072VIF3|A0A072VIF3_MEDTR Exostosin family protein; Found in the gene: LotjaGi5g1v0148800 | 16 | ||
| – | Exostosin family protein; TAIR: AT3G57630.1 exostosin family protein; Swiss-Prot: sp|Q6NMM8|F8H_ARATH Probable glucuronoxylan glucuronosyltransferase F8H; TrEMBL-Plants: tr|A0A072VIF3|A0A072VIF3_MEDTR Exostosin family protein; Found in the gene: LotjaGi5g1v0148800 | 16 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00055 | CDD | 1 | 7.14 |